Abstract

The specific objective of this contract is to develop and implement Quantative Structure Activity Relationships (QSAR) analyses which relate functions of chemical structures to measure of biological activity. These analyses will be used to develop the mathematical equations, or """"""""Structure activity relationships"""""""" of approximately 14,000 compounds which will have been screened for anticonvulsant activity by the ADD program of the NINDS. All structure activity analyses will be used in the evaluation of potential drugs for treatment of epilepsy.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research and Development Contracts (N01)
Project #
N01NS002398-005
Application #
2321457
Study Section
Project Start
1990-09-30
Project End
1993-09-29
Budget Start
1992-09-30
Budget End
1993-09-29
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Minnesota Duluth
Department
Type
Organized Research Units
DUNS #
071508873
City
Duluth
State
MN
Country
United States
Zip Code
55812