Abstract

Evaluate the effects of long-term phenobarbital treatment in children aged one to five years who have had febrile convulsions. The primary objective is to assess the effects over time of phenobarbital on behavior and cognitive function. A secondary objective is to evaluate the effects of febrile seizure recurrence on behavior and cognitive function, and to compare these effects of prophylactic treatment.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research and Development Contracts (N01)
Project #
N01NS022395-010
Application #
3669273
Study Section
Project Start
1982-05-01
Project End
1985-05-31
Budget Start
1985-05-21
Budget End
1985-05-31
Support Year
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Sulzbacher, S; Farwell, J R; Temkin, N et al. (1999) Late cognitive effects of early treatment with phenobarbital. Clin Pediatr (Phila) 38:387-94
Farwell, J R; Blackner, G; Sulzbacher, S et al. (1994) First febrile seizures. Characteristics of the child, the seizure, and the illness. Clin Pediatr (Phila) 33:263-7
Farwell, J R; Lee, Y J; Hirtz, D G et al. (1990) Phenobarbital for febrile seizures--effects on intelligence and on seizure recurrence. N Engl J Med 322:364-9