The Immune Epitope Database and Analysis Program contains extensively curated antibody and T cell epitope information from the published literature, as well as tools to predict antibody and T cell epitopes or visualization/mapping of epitopes onto known protein structures. Over 4,000 references have been curated into the IEDB, including all of the epitope literature for NIAID Category A, B, and C Priority Pathogens. (Category A, B, and C Prioroty Pathogens include among others Yersinia pestis, smallpox, and influenza, and rabies virus.) This information represents over 5,000 unique antibody epitopes, greater than 16,000 unique T cell epitopes, and is continually updated. In addition, the IEDB hosts a series of epitope analysis tools such as antibody and T cell epitope prediction algorithms, epitope homology discovery, HLA frequency analysis, and 3D epitope viewer/protein mapping tools. Curation of data relating to malaria, hepatitis B, Clostridium tetani, Leishmania, Candida albicans of herpes viruses are in maintenance mode or almost complete.
