The goal of this contract is to provide support of National Toxicology Program (NTP) hazard identification (or hazard assessment) activities targeted toward the prevention of diseases or adverse effects caused by environmental exposure to chemical or physical agents. This project involves prechronic and chronic studies of selected chemicals via inhalation exposure. The 14-day and 90 day studies hve been completed and reports have been submitted for vinylidene chloride and alpha-pinene. The 2-year study of vinylidene chloride has been completed and reported. The 2-year study for alpha-pinene has been canceled.Keywords Carcinogenicity; toxicity; bioassay; F344 rats; B6C3F1 mice; vinylidene chloride; alpha-pinene
