The goal of the NHGRI Sample Repository for Human Genetic Research is to provide a readilyaccessible, centralized resource for genetic studies in a number of areas, including theInternational HapMap Project and samples with well-documented phenotypes. To this end, theNHGRI Repository will prepare and distribute cell lines and DNA with associated clinical,molecular and familial data to the scientific community. A key aim is to provide a resource forscientists where there are continuing long-term interactions with the communitites who donatedthe samples. This interaction with the community will include visits with the communities throughCommunity Advisory Groups, periodic news letters and quarterly reports to the communities.