The principal objectives of this contract are the web-based wordwide acquisition and distribution of small molecule organic compounds for pre-clinical testing in NCI anti-cancer screening programs and also distribution to the external research community. The contract provides for safe and efficient receipt, storage, inventory, distribution, plating, disposal and documentation of synthetic compounds, purified natural products and also a limited number of bulk drugs. These tasks must be executed in compliance with all local, state and Federal regulations. This contract is also responsible for the management of supplier information, correspondence to and from the compound suppliers, for maintenance and updating chemical databases, systematic file and record keeping and reacquistion of needed samples for continuing chemical and/or biological studies.