Researchers from multiple medical, nursing, and social/behavioral science specialties from three major research institutions propose to establish a coordinated mechanism for present and future research to identify and measure the modifiable factors affecting health status and health care of chronically ill elders. The research being currently proposed focuses on a wide range of potentially modifiable factors including: hormonal predispositions for hip fracture; changes in renal and cognitive functions among older diabetics; metabolism of nonsteroidal drugs used in arthritis; identification of sleep disorders among nursing home residents; cognitive training of mildly demented nursing home residents; and nursing requirements of patient care in nursing homes. Current research (TNH) sites to be shared by these studies include one free-standing nursing home, two continuum-of-care residential facilities including skilled nursing units, and a community health service with a large number of older members; acute care hospital patients will also be used for individual proposals. Recruitment of subjects and other research sites, liaison with staff and resident councils, centralized storage of basic standardized information and data management/analysis functions will be performed by center core staff. Future research will be developed by soliciting and reviewing proposals, utilizing Pilot Projects and other funding support. A research advisory committee will assist in the review of subsequent proposals. A clinical care advisory committee will assist with future clinical issues. A plan for analyzing shared data will be designed. TNH Council will make policy; weekly seminars will share findings.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG004458-04
Application #
3090898
Study Section
Aging Review Committee (AGE)
Project Start
1985-03-01
Project End
1990-02-28
Budget Start
1988-03-01
Budget End
1989-02-28
Support Year
4
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Bliwise, D L (1993) Sleep in normal aging and dementia. Sleep 16:40-81
Bachrach, L K; Katzman, D K; Litt, I F et al. (1991) Recovery from osteopenia in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab 72:602-6
Bliwise, D L; Nekich, J C; Dement, W C (1991) Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population. Chest 99:600-8
Bliwise, D L; Carskadon, M A; Seidel, W F et al. (1991) MSLT-defined sleepiness and neuropsychological test performance do not correlate in the elderly. Neurobiol Aging 12:463-8
Bachrach, L K; Guido, D; Katzman, D et al. (1990) Decreased bone density in adolescent girls with anorexia nervosa. Pediatrics 86:440-7
Woodward, S H; Owens, J; Thompson, L W (1990) Word-to-word variation in ERP component latencies: spoken words. Brain Lang 38:488-503
Myers, B D (1990) Pathophysiology of proteinuria in diabetic glomerular disease. J Hypertens Suppl 8:S41-6
Marcus, R; Butterfield, G; Holloway, L et al. (1990) Effects of short term administration of recombinant human growth hormone to elderly people. J Clin Endocrinol Metab 70:519-27
Bliwise, D L; Bevier, W C; Bliwise, N G et al. (1990) Systematic 24-hr behavioral observations of sleep and wakefulness in a skilled-care nursing facility. Psychol Aging 5:16-24
Coulston, A M; Mandelbaum, D; Reaven, G M (1990) Dietary management of nursing home residents with non-insulin-dependent diabetes mellitus. Am J Clin Nutr 51:67-71

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