Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG020641-05
Application #
7499389
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (O2))
Project Start
2007-04-01
Project End
2008-01-31
Budget Start
2007-04-01
Budget End
2008-01-31
Support Year
5
Fiscal Year
2007
Total Cost
$113,387
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Type
DUNS #
122452563
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Shmookler Reis, Robert J; Xu, Lulu; Lee, Hoonyong et al. (2011) Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants. Aging (Albany NY) 3:125-47
Tazearslan, Cagda?; Ayyadevara, Srinivas; Bharill, Puneet et al. (2009) Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance. PLoS Genet 5:e1000452
Ayyadevara, Srinivas; Tazearslan, Cagda?; Bharill, Puneet et al. (2009) Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan. Aging Cell 8:706-25
Shmookler Reis, Robert J; Bharill, Puneet; Tazearslan, Cagdas et al. (2009) Extreme-longevity mutations orchestrate silencing of multiple signaling pathways. Biochim Biophys Acta 1790:1075-83
Ounpraseuth, Songthip; Rafferty, Tonya M; McDonald-Phillips, Rachel E et al. (2009) A method to quantify mouse coat-color proportions. PLoS One 4:e5414
Singh, Sharda P; Niemczyk, Maciej; Saini, Deepti et al. (2008) Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. Biochemistry 47:3900-11
Chae, Minho; Shmookler Reis, Robert J; Thaden, John J (2008) An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass spectrometry peaks. BMC Bioinformatics 9 Suppl 9:S15
Leakey, Tatiana I; Zielinski, Jerzy; Siegfried, Rachel N et al. (2008) A simple algorithm for quantifying DNA methylation levels on multiple independent CpG sites in bisulfite genomic sequencing electropherograms. Nucleic Acids Res 36:e64
Zimniak, Piotr (2008) Detoxification reactions: relevance to aging. Ageing Res Rev 7:281-300
Ayyadevara, Srinivas; Dandapat, Abhijit; Singh, Sharda P et al. (2007) Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Mech Ageing Dev 128:196-205

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