Abstract

The overall objective of the Transgenic and Mutant Mouse Core is to provide Program Project investigators with the ability to utilize animal models in the execution of their proposed research projects as well as establish new animal models for the investigation of the molecular involved in skin and appendage development. The Transgenic and Mutant Mouse Core will minimize the cost of utilizing animal models in this Program Project by consolidating the equipment, expertise and animal resource. This will ensure an efficient use of animal research at minimal cost.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Program Projects (P01)
Project #
5P01AR047898-02
Application #
6652192
Study Section
Special Emphasis Panel (ZAR1)
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Type
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Hoelzl, Maria A; Heby-Henricson, Karin; Gerling, Marco et al. (2017) Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Dev Biol 429:132-146
Rice, Robert H; Durbin-Johnson, Blythe P; Ishitsuka, Yosuke et al. (2016) Proteomic Analysis of Loricrin Knockout Mouse Epidermis. J Proteome Res 15:2560-6
Ishitsuka, Yosuke; Huebner, Aaron J; Rice, Robert H et al. (2016) Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin. J Invest Dermatol 136:1656-1663
Zhang, Cong; Large, Michael J; Duggavathi, Raj et al. (2013) Liver receptor homolog-1 is essential for pregnancy. Nat Med 19:1061-6
Fiaschi, Marie; Kolterud, Asa; Nilsson, Mats et al. (2011) Targeted expression of GLI1 in the salivary glands results in an altered differentiation program and hyperplasia. Am J Pathol 179:2569-79
Dai, Daisy; Zhu, Huiping; Wlodarczyk, Bogdan et al. (2011) Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol 131:302-10
Honeycutt, Kimberly A; Waikel, Rebekah L; Koster, Maranke I et al. (2010) The effect of c-myc on stem cell fate influences skin tumor phenotype. Mol Carcinog 49:315-9
Jaks, Viljar; Kasper, Maria; Toftgard, Rune (2010) The hair follicle-a stem cell zoo. Exp Cell Res 316:1422-8
Koster, Maranke I; Marinari, Barbara; Payne, Aimee S et al. (2009) DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A 149A:1942-7
Jia, Jinping; Kolterud, Asa; Zeng, Huiqing et al. (2009) Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia. Dev Biol 330:452-60

Showing the most recent 10 out of 53 publications