Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Program Projects (P01)
Project #
5P01AR049363-05
Application #
7504522
Study Section
Special Emphasis Panel (ZAR1-TAS-A (O1))
Project Start
2007-09-01
Project End
2008-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
5
Fiscal Year
2007
Total Cost
$247,155
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Teramachi, Jumpei; Hiruma, Yuko; Ishizuka, Seiichi et al. (2013) Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease. J Bone Miner Res 28:1489-500
Kurihara, Noriyoshi; Hiruma, Yuko; Yamana, Kei et al. (2011) Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease. Cell Metab 13:23-34
Sundaram, Kumaran; Senn, Joseph; Yuvaraj, Sambandam et al. (2009) FGF-2 stimulation of RANK ligand expression in Paget's disease of bone. Mol Endocrinol 23:1445-54
Hiruma, Yuko; Kurihara, Noriyoshi; Subler, Mark A et al. (2008) A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment. Hum Mol Genet 17:3708-19
Sundaram, Kumaran; Mani, Santhosh K; Kitatani, Kazuyuki et al. (2008) DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells. J Cell Biochem 103:1747-59
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Ishizuka, Seiichi; Kurihara, Noriyoshi; Hiruma, Yuko et al. (2008) 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells. J Steroid Biochem Mol Biol 110:269-77
Kurihara, Noriyoshi; Hiruma, Yuko; Zhou, Hua et al. (2007) Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J Clin Invest 117:133-42
Reddy, S V (2006) Etiologic factors in Paget's disease of bone. Cell Mol Life Sci 63:391-8
Kurihara, Noriyoshi; Zhou, Hua; Reddy, Sakamuri V et al. (2006) Expression of measles virus nucleocapsid protein in osteoclasts induces Paget's disease-like bone lesions in mice. J Bone Miner Res 21:446-55

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