Abstract

The overall objective of this program project is to explore and improve the utilization of radiation and combinations of radiation and other modalities in order to increase the cure of cancer and to evaluate the long term effects of radiation and combinations of radiation and other modalities. These objectives will be achieved by: a. Continuing the development of a specialized Radiation Oncology Research and Clinical Program Project. This Project will continue to develop an overall integrated program for research in radiation biology, radiation immunology, radiation physics and related basic sciences and to promote, enhance and stimulate the investigation of the basic mechanisms of radiation, and combination of radiation and other agents in the treatment and control of cancer and evaluation of long term effect with the goal of possible human application in mind. b. Continuing to expand our overall integrated program to carry out clinical research utilizing radiation combined with other agents to improve results in the treatment of human cancer and to integrate information obtained from basic research whenever possible to the clinical treatment. c. Continuing to provide a center for demonstration and teaching of the appropriate advanced therapeutic methods and techniques so that these can be taught to physicians, medical students, and support personnel of this area and thus be made available to patients. d. Continuing to provide and further develop our Training Program in radiation oncology for graduate and undergrade physicians, technicians and nurses for this region.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA015548-10
Application #
3092669
Study Section
Clinical Cancer Program Project Review Committee (CCP)
Project Start
1979-04-01
Project End
1986-05-31
Budget Start
1985-06-01
Budget End
1986-05-31
Support Year
10
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Lee, C K; Aeppli, D M; Bloomfield, C D et al. (1987) Hodgkin's disease: a reassessment of prognostic factors following modification of radiotherapy. Int J Radiat Oncol Biol Phys 13:983-91
Werner, B L; Das, I J (1987) Dose distributions in regions containing beta sources: plane interface in a homogeneous medium. Med Phys 14:797-806
Gerbi, B J; Levitt, S H (1987) Treatment planning of radiotherapy for lung cancer. Front Radiat Ther Oncol 21:152-80
Kim, T H; Ramsay, N K; Steeves, R A et al. (1987) Intermittent central nervous system irradiation and intrathecal chemotherapy for central nervous system leukemia in children. Int J Radiat Oncol Biol Phys 13:1451-5
Gerbi, B J; Khan, F M (1987) The polarity effect for commercially available plane-parallel ionization chambers. Med Phys 14:210-5
Levitt, S H; Lee, C K; Aeppli, D M et al. (1987) Radical treatment of Hodgkin disease with radiation therapy: results of a 15-year clinical trial. The 1985 Erskine lecture. Radiology 162:623-30
Werner, B L; Das, I J; Khan, F M et al. (1987) Dose perturbations at interfaces in photon beams. Med Phys 14:585-95
Meigooni, A S; Das, I J (1987) Parametrization of depth dose for electron beams. Phys Med Biol 32:761-8
Tang, W L; Khan, F M; Gerbi, B J (1986) Validity of lung correction algorithms. Med Phys 13:683-6
Potish, R A; Twiggs, L B; Adcock, L L et al. (1986) Effect of cis-platinum on tolerance to radiation therapy in advanced cervical cancer. Am J Clin Oncol 9:387-91

Showing the most recent 10 out of 23 publications