Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA021112-09
Application #
4690894
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Merlini, G; Bruening, R; Kyle, R A et al. (1990) The second riboflavin-binding myeloma IgG lambdaDOT. I. Biochemical and functional characterization. Mol Immunol 27:385-94
Kabat, E A (1988) Antibody combining sites: how much of the antibody repertoire are we seeing? How does it influence our understanding of the structural and genetic basis of antibody complimentarity? Adv Exp Med Biol 228:1-45
Berman, J E; Mellis, S J; Pollock, R et al. (1988) Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus. EMBO J 7:727-38
Kabat, E A; Liao, J; Osserman, E F et al. (1988) The epitope associated with the binding of the capsular polysaccharide of the group B meningococcus and of Escherichia coli K1 to a human monoclonal macroglobulin, IgMNOV. J Exp Med 168:699-711
Bellon, B; Manheimer-Lory, A; Monestier, M et al. (1987) High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains. J Clin Invest 79:1044-53
Osserman, E F; Merlini, G; Butler Jr, V P (1987) Multiple myeloma and related plasma cell dyscrasias. JAMA 258:2930-7
Reth, M G; Jackson, S; Alt, F W (1986) VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments. EMBO J 5:2131-8
Kabat, E A; Nickerson, K G; Liao, J et al. (1986) A human monoclonal macroglobulin with specificity for alpha(2----8)-linked poly-N-acetyl neuraminic acid, the capsular polysaccharide of group B meningococci and Escherichia coli K1, which crossreacts with polynucleotides and with denatured DNA. J Exp Med 164:642-54
Merlini, G; Farhangi, M; Osserman, E F (1986) Monoclonal immunoglobulins with antibody activity in myeloma, macroglobulinemia and related plasma cell dyscrasias. Semin Oncol 13:350-65
Bonagura, V R; Agostino, N; Crow, M K et al. (1985) Anti-immunoglobulin stimulation of human B lymphocytes is inhibited by anti-class II major histocompatibility complex antibodies. Cell Immunol 96:442-7

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