This is a program project proposal to establish a multidisciplinary clinical research program aimed at focusing a variety of specific laboratory and clinical disciplines on investigating the disease leukemia.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA028153-07
Application #
3093229
Study Section
(SRC)
Project Start
1980-07-01
Project End
1989-01-31
Budget Start
1987-02-01
Budget End
1988-01-31
Support Year
7
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Hospitals
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Skinner, W L; Murray, D; Kohli, V et al. (1990) Resistance to 4-(9-acridinylamino) methanesulphon-m-anisidide (m-AMSA) in human myeloid leukaemia. Br J Cancer 61:51-5
Kantarjian, H M; Keating, M J; Walters, R S et al. (1989) Phase II study of low-dose continuous infusion homoharringtonine in refractory acute myelogenous leukemia. Cancer 63:813-7
Estey, E; Smith, T L; Keating, M J et al. (1989) Prediction of survival during induction therapy in patients with newly diagnosed acute myeloblastic leukemia. Leukemia 3:257-63
Kantarjian, H M; Walters, R S; Keating, M J et al. (1989) Experience with vincristine, doxorubicin, and dexamethasone (VAD) chemotherapy in adults with refractory acute lymphocytic leukemia. Cancer 64:16-22
Keating, M J; Kantarjian, H; Smith, T L et al. (1989) Response to salvage therapy and survival after relapse in acute myelogenous leukemia. J Clin Oncol 7:1071-80
Walters, R S; Kantarjian, H M; Keating, M J et al. (1988) Mitoxantrone and high-dose cytosine arabinoside in refractory acute myelogenous leukemia. Cancer 62:677-82
Zander, A R; Keating, M; Dicke, K et al. (1988) A comparison of marrow transplantation with chemotherapy for adults with acute leukemia of poor prognosis in first complete remission. J Clin Oncol 6:1548-57
Hittelman, W N; Agbor, P; Petkovic, I et al. (1988) Detection of leukemic clone maturation in vivo by premature chromosome condensation. Blood 72:1950-60
Kantarjian, H M; Walters, R S; Smith, T L et al. (1988) Identification of risk groups for development of central nervous system leukemia in adults with acute lymphocytic leukemia. Blood 72:1784-9
Keating, M J; Smith, T L; Kantarjian, H et al. (1988) Cytogenetic pattern in acute myelogenous leukemia: a major reproducible determinant of outcome. Leukemia 2:403-12

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