Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
3P01DK043078-04S1
Application #
3095655
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1990-09-01
Project End
1995-02-28
Budget Start
1993-06-07
Budget End
1994-02-28
Support Year
4
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Zekzer, D; Wong, F S; Ayalon, O et al. (1998) GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice. J Clin Invest 101:68-73
Zekzer, D; Wong, F S; Wen, L et al. (1997) Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mouse. Diabetes 46:1124-32
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von Herrath, M G; Guerder, S; Lewicki, H et al. (1995) Coexpression of B7-1 and viral (""self"") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. Immunity 3:727-38
Guerder, S; Flavell, R A (1995) Costimulation in tolerance and autoimmunity. Int Rev Immunol 13:135-46

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