Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
3P01ES003816-03S1
Application #
3095894
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1986-09-01
Project End
1991-08-31
Budget Start
1989-09-01
Budget End
1991-08-31
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Schools of Pharmacy
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90033
Cadenas, E; Hochstein, P; Ernster, L (1992) Pro- and antioxidant functions of quinones and quinone reductases in mammalian cells. Adv Enzymol Relat Areas Mol Biol 65:97-146
Sato, Y; Eddy, L; Hochstein, P (1991) Comparative cardiotoxicity of doxorubicin and a morpholino anthracycline derivative (KRN8602). Biochem Pharmacol 42:2283-7
Robison, T W; Sevanian, A; Forman, H J (1990) Inhibition of arachidonic acid release by nordihydroguaiaretic acid and its antioxidant action in rat alveolar macrophages and Chinese hamster lung fibroblasts. Toxicol Appl Pharmacol 105:113-22
Arduini, A; Eddy, L; Hochstein, P (1990) The reduction of ferryl myoglobin by ergothioneine: a novel function for ergothioneine. Arch Biochem Biophys 281:41-3
Galaris, D; Sevanian, A; Cadenas, E et al. (1990) Ferrylmyoglobin-catalyzed linoleic acid peroxidation. Arch Biochem Biophys 281:163-9
Chen, Y X; Yang, D C; Brown, A B et al. (1990) Activation of a membrane-associated phosphatidylinositol kinase through tyrosine-protein phosphorylation by naphthoquinones and orthovanadate. Arch Biochem Biophys 283:184-92
Sevanian, A; Nordenbrand, K; Kim, E et al. (1990) Microsomal lipid peroxidation: the role of NADPH--cytochrome P450 reductase and cytochrome P450. Free Radic Biol Med 8:145-52
Yang, D C; Brown, A B; Chan, T M (1989) Stimulation of tyrosine-specific protein phosphorylation and phosphatidylinositol phosphorylation by orthovanadate in rat liver plasma membrane. Arch Biochem Biophys 274:659-62
Galaris, D; Cadenas, E; Hochstein, P (1989) Redox cycling of myoglobin and ascorbate: a potential protective mechanism against oxidative reperfusion injury in muscle. Arch Biochem Biophys 273:497-504
Galaris, D; Cadenas, E; Hochstein, P (1989) Glutathione-dependent reduction of peroxides during ferryl- and met-myoglobin interconversion: a potential protective mechanism in muscle. Free Radic Biol Med 6:473-8

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