The Statistics Core is new and will be led by Dr. Laurel Beckett, Biostatistics Division Chief. The core will coordinate all the CCEH needs for experimental design, data integration, and statistical analysis. The Core advises on design of studies, linkage of analytic databases across cores and projects, mathematical and statistical analyses, and mechanisms to allow researchers and decision makers to visualize probable consequences of alternative mechanistic models. Dr. Beckett, the Core Leader, has worked with the CCEH since its inception. Her methodological expertise lies in longitudinal cohort studies and modeling of multivariate change processes, and she has many years of experience in collaborative research in neurodegenerative and neurodevelopmental diseases and in studies of growth and development. Dr. Lihong Qi is a new faculty member whose expertise is in biostatistics and has extensive training in conducting methodological research on high-dimensional genetic association single nucleotide polymorphism (SNP) studies. Dr. Nguyen's expertise is in the analysis of high dimensional data, especially genomic expression data, false discovery rate in genomics applications, and covariate-adjusted regression and correlation analysis. Additional expertise is available to Center researchers through the Division of Biostatistics, whose 10 faculty members include experts in genomics, bioinformatics, missing data in longitudinal studies, neuroimaging, and time-to-event data. Dr. Hertz-Picciotto, Deputy Director and Project 1 leader, is an experienced epidemiologic methodologist who will act as the CCEH Liaison to the Statistics Core.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES011269-09
Application #
7900935
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
9
Fiscal Year
2009
Total Cost
$15,567
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Jones, Karen L; Pride, Michael C; Edmiston, Elizabeth et al. (2018) Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism. Mol Psychiatry :
Rose, Destanie R; Yang, Houa; Serena, Gloria et al. (2018) Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms. Brain Behav Immun 70:354-368
Zheng, Jing; Chen, Juan; Zou, Xiaohan et al. (2018) Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology 70:112-121
Shin, Hyeong-Moo; Schmidt, Rebecca J; Tancredi, Daniel et al. (2018) Prenatal exposure to phthalates and autism spectrum disorder in the MARBLES study. Environ Health 17:85
Keil, Kimberly P; Miller, Galen W; Chen, Hao et al. (2018) PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Arch Toxicol 92:3163-3173
Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim et al. (2018) Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol 52:5469-5478
Chen, Xiaopeng; Walter, Kyla M; Miller, Galen W et al. (2018) Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr 32:e4185
Jones, Karen L; Van de Water, Judy (2018) Maternal autoantibody related autism: mechanisms and pathways. Mol Psychiatry :
Kerin, Tara; Volk, Heather; Li, Weiyan et al. (2018) Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder. J Autism Dev Disord 48:137-150
Miller, Galen W; Chandrasekaran, Vidya; Yaghoobi, Bianca et al. (2018) Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity. Neurotoxicology 67:102-111

Showing the most recent 10 out of 327 publications