Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM046006-06
Application #
2183604
Study Section
Special Emphasis Panel (ZRG7-SSS-3 (12))
Project Start
1991-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Kiely, J; Haase, S B; Russell, P et al. (2000) Functions of fission yeast orp2 in DNA replication and checkpoint control. Genetics 154:599-607
Kaiser, P; Flick, K; Wittenberg, C et al. (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 102:303-14
Kesti, T; Flick, K; Keranen, S et al. (1999) DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability. Mol Cell 3:679-85
Hengst, L; Gopfert, U; Lashuel, H A et al. (1998) Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1). Genes Dev 12:3882-8
Stuart, D; Wittenberg, C (1998) CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint. Genes Dev 12:2698-710
Flick, K; Chapman-Shimshoni, D; Stuart, D et al. (1998) Regulation of cell size by glucose is exerted via repression of the CLN1 promoter. Mol Cell Biol 18:2492-501
Niculescu 3rd, A B; Chen, X; Smeets, M et al. (1998) Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol 18:629-43
Lukas, J; Herzinger, T; Hansen, K et al. (1997) Cyclin E-induced S phase without activation of the pRb/E2F pathway. Genes Dev 11:1479-92
Furnari, B A; Russell, P; Leatherwood, J (1997) Pch1(+), a second essential C-type cyclin gene in Schizosaccharomyces pombe. J Biol Chem 272:12100-6
Kovelman, R; Russell, P (1996) Stockpiling of Cdc25 during a DNA replication checkpoint arrest in Schizosaccharomyces pombe. Mol Cell Biol 16:86-93

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