Abstract

OFTHEOVERALLCOMPONENT Althoughnon?communicablediseases(NCD)representover80%ofthediseaseburdenin SouthAmerica,mosthealthresourcesintheregionarestilldedicatedtoinfectiousdiseaseand maternalandchildhealth.Astheregioncompletesitsepidemiological,demographicand nutritionaltransition,thereisanurgentneedtoimprovestrategiestoreducetheincreasing burdenofNCD.ThisapplicationdescribesthedesignanddevelopmentoftheSouthAmerican CenterofResearchExcellenceinChronicNon?communicablediseases(SACREN)toestablish researchactivitiesrelatedtocancerandcardiovasculardiseases(CVD)preventionandcontrol. TheCenterwillbehostedbytwoformerNationalHeart,LungBloodInstitute(NIH/NHLBI) CentersofExcellence(COE):TheSouthAmericanCenterofExcellenceforChronicdiseases (CESCAS)attheInstituteforClinicalEffectivenessandHealthPolicy(IECS)inBuenosAires, ArgentinawhichcoverstheSouthernConeofLatinAmerica(Argentina,ChileandUruguay) andtheCRONICASCenterofExcellenceinChronicDiseasesattheUniversidadPeruana CayetanoHeredia(UPCH),inPeru,boththrivingresearchandprovidingarichenvironmentfor researchcapacitybuildingintheregion.Infact,bothteams,whicharecurrentlysupportedby NIHandotherinternationalandnationalfunders,havearemarkabletrackrecordofsuccessful researchintermsofpublicationsandgrants.Moreimportantly,takenthistothenextlevelto establishSACREN,bothCESCASandCRONICASwillpartnerwiththeDivisionofPopulation SciencesatDana?FarberCancerInstitute,(DFCI)andHarvardMedicalSchool(HMS),where bothwillcontributetheirworld?classexpertiseandleadershipinbuildingcapacityforcancer researchthatspansthespectrumfrompreventiontotreatment.SACRENwilltakingadvantage ofthecapacitybuildingexperienceofthethreepartnersandestablishsharedresourcesand facilitiestoallowenhancinginnovativepopulation,translational(T4),clinical,implementation andpolicyresearchtocountercancerandCVD.Forthisplanninggrant,SACRENwilldevelop tworesearchprogramsincancerandCVDepidemiology,buildingontheintegrationofthe population?basedcohortsinArgentina,Chile,PeruandUruguay.Inaddition,itwillundertakea pilotcollaborativeprojectongeo?mappingofGBCandGCinSouthAmerica,basedonGIS technology.SACRENwilldevelopitsinitialactivitiesinArgentina,Chile,PeruandUruguay,and willlaterexpandtoBoliviaandParaguay.Inthisregard,ourproposalhasbeenendorsedby thecurrentMinistersofHealthofArgentinaandPeruandtheauthoritiesofthenational cancerinstitutesand/ortheMinistriesofHealthofallcountriesinvolved

Public Health Relevance

OFTHEOVERALLCOMPONENT ThegoalofthisproposalistodeveloptheSouthAmericanCenterofResearchExcellencein ChronicNon?communicablediseases(SACREN)toestablishresearchprogramsandcapacity buildingactivitiesrelatedtocancerandcardiovasculardiseases(CVD)preventionandcontrol inSouthAmerica.SACRENwilldevelopitsinitialactivitiesinArgentina,Chile,Peruand Uruguay,andwilllaterexpandtoBoliviaandParaguay.Inthisregard,ourproposalhasbeen endorsedbythecurrentMinistersofHealthofArgentinaandPeruandtheauthoritiesofthe nationalcancerinstitutesand/ortheMinistriesofHealthofallcountriesinvolved.The overarchingaimistocreateaplatformtofacilitateapolicydialogueinformedbynationaland regionalresearchneedsandgapstoreducecancerandCVD

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants (P20)
Project #
5P20CA217231-02
Application #
9560695
Study Section
Special Emphasis Panel (ZCA1)
Program Officer
Silkensen, Shannon M
Project Start
2017-09-15
Project End
2019-08-31
Budget Start
2018-09-01
Budget End
2019-08-31
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
Instituto de Efectividad Clinica Y Sanit
Department
Type
DUNS #
978136497
City
Ciudad de Buenos Aires
State
Country
Argentina
Zip Code
C1414CPV

  Publications

Benziger, Catherine P; Zavala-Loayza, José Alfredo; Bernabe-Ortiz, Antonio et al. (2018) Low prevalence of ideal cardiovascular health in Peru. Heart 104:1251-1256