? Developmental Research Project Program The overall mission of the Developmental Research Project Program (DRPP) is to execute a competitive Pilot Project research program that leads to research independence and further builds research capability, capacity and engagement in DE-INBRE thematic areas of cancer, cardiovascular and neuroscience. The DRPP?s goal is to ensure that Delaware takes the next major step toward the State?s goal of building a diverse, self-sustaining biomedical research enterprise, thereby improving health care and promoting health-based economic development. The DE-INBRE DRPP?s support of Pilot Project investigators has been a key resource for establishing research capabilities across the state. The DRPP is primarily intended to support the efforts of Delaware?s junior biomedical investigators to become independent investigators. The pilot program employs novel approaches to increase the research opportunities for young faculty. Under the ongoing program, the Research Independence Award provides support to a cohort of new and/or early- stage investigators. The goal is for the junior investigator to effectively utilize the resources of Delaware?s biomedical research network ? as well as the scientific and technical strengths of collaborating investigators and/or mentors to engage undergraduate students ? while the investigator advances towards obtaining research independence by receiving an NIH R01 or institutionally equivalent award. In INBRE IV, a new Research Engagement Award mechanism targeting the NIH R15-like grants will be implemented. The purpose is to increase the collaborative research engagement of faculty and undergraduate students at Delaware?s Primarily Undergraduate Institutions (PUIs). It is intended to serve as a stepping stone towards research independence for PUI faculty to obtain NIH R15 or like funding, to compete effectively for the DRPP Research Independence Award, and to ultimately obtain research independence.
Specific Aims 1. Build and strengthen Delaware?s biomedical research capacity and capability in cancer, cardiovascular health, and neuroscience within the DE-INBRE network. 2. Increase the research base of investigators receiving grant funding in cancer, cardiovascular health, and neuroscience. 3. Engage investigators and students at Delaware?s PUIs with key network resources.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103446-20
Application #
9930653
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Delaware
Department
Type
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Melamed, Jilian R; Kreuzberger, Nicole L; Goyal, Ritu et al. (2018) Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery. Mol Ther Nucleic Acids 12:207-219
D'Souza, Malcolm J; Shuman, Kevin E; Wentzien, Derald E et al. (2018) Working with the Wesley College Cannon Scholar Program: Improving Retention, Persistence, and Success. J STEM Educ 19:31-40
Lau, Hang Kuen; Paul, Alexandra; Sidhu, Ishnoor et al. (2018) Microstructured Elastomer-PEG Hydrogels via Kinetic Capture of Aqueous Liquid-Liquid Phase Separation. Adv Sci (Weinh) 5:1701010
Nemani, Neeharika; Carvalho, Edmund; Tomar, Dhanendra et al. (2018) MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress. Cell Rep 23:1005-1019
Vest, Michael T; Papas, Mia A; Shapero, Mary et al. (2018) Characteristics and Outcomes of Adult Inpatients With Malnutrition. JPEN J Parenter Enteral Nutr 42:1009-1016
Minker, Katharine R; Biedrzycki, Meredith L; Kolagunda, Abhishek et al. (2018) Semiautomated confocal imaging of fungal pathogenesis on plants: Microscopic analysis of macroscopic specimens. Microsc Res Tech 81:141-152
Papah, Michael B; Brannick, Erin M; Schmidt, Carl J et al. (2018) Gene expression profiling of the early pathogenesis of wooden breast disease in commercial broiler chickens using RNA-sequencing. PLoS One 13:e0207346
Goyal, Ritu; Kapadia, Chintan H; Melamed, Jilian R et al. (2018) Layer-by-layer assembled gold nanoshells for the intracellular delivery of miR-34a. Cell Mol Bioeng 11:383-396
Hudson, Devin A; Caplan, Jeffrey L; Thorpe, Colin (2018) Designing Flavoprotein-GFP Fusion Probes for Analyte-Specific Ratiometric Fluorescence Imaging. Biochemistry 57:1178-1189
Cogburn, Larry A; Trakooljul, Nares; Chen, Chuming et al. (2018) Transcriptional profiling of liver during the critical embryo-to-hatchling transition period in the chicken (Gallus gallus). BMC Genomics 19:695

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