? While much progress has been made to control preventable infectious diseases, infections remain a major cause of morbidity and mortality. Many of the traditional treatments for common infections are no longer effective because of the fast-growing problem of antimicrobial resistance, first associated with hospitals but increasingly widespread in the community. Antibiotic resistance is now a global problem of major concern. The ultimate goal of this proposed Center for Interdisciplinary Research on Antimicrobial Resistance (CIRAR) is to develop strategies to implement and evaluate a long term collaborative program of interdisciplinary research on reducing antimicrobial resistance.
The specific aims of the CIRAR are: (1) To plan, implement, and evaluate outcomes of a core program and curriculum to prepare medical researchers to conduct interdisciplinary research; (2) To develop the expertise of CIRAR investigators in interdisciplinary research; (3) To conduct and evaluate outcomes of interdisciplinary demonstration projects related to the prevention and control of antimicrobial resistance; (4) To implement dissemination and implementation strategies that maximize the sustainability and expansion of CIRAR's interdisciplinary research; and (5) To formalize plans for a sustainable Interdisciplinary Research Consortium for Antimicrobial Resistance. The first component of the Center is the development and implementation of formal training for conducting interdisciplinary research which will be incorporated into several ongoing programs within the institution and made available by internet. In Years 2 and 3 the interdisciplinary research curriculum will be further disseminated. The second CIRAR component is the development of interdisciplinary demonstration projects designed to rationalize antimicrobial use and reduce antimicrobial resistance. In the final year, plans for a sustainable Consortium on antimicrobial resistance will be formalized. ? ?

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR020616-03
Application #
7086267
Study Section
Special Emphasis Panel (ZRR1-BT-8 (01))
Program Officer
Farber, Gregory K
Project Start
2004-09-20
Project End
2009-07-31
Budget Start
2006-08-01
Budget End
2009-07-31
Support Year
3
Fiscal Year
2006
Total Cost
$582,984
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Nursing
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Kelly, A M; Smith, B; Luo, Z et al. (2016) Discordance between patient and clinician reports of adverse reactions to MDR-TB treatment. Int J Tuberc Lung Dis 20:442-7
Pereira, Marcus R; Scully, Brendan F; Pouch, Stephanie M et al. (2015) Risk factors and outcomes of carbapenem-resistant Klebsiella pneumoniae infections in liver transplant recipients. Liver Transpl 21:1511-9
Pogorzelska, Monika; Stone, Patricia W; Furuya, E Yoko et al. (2011) Impact of the ventilator bundle on ventilator-associated pneumonia in intensive care unit. Int J Qual Health Care 23:538-44
Clock, Sarah A; Cohen, Bevin; Behta, Maryam et al. (2010) Contact precautions for multidrug-resistant organisms: Current recommendations and actual practice. Am J Infect Control 38:105-11
Patel, Sameer J; Rosen, Emily; Zaoutis, Theoklis et al. (2010) Neonatologists' perceptions of antimicrobial resistance and stewardship in neonatal intensive care units. Infect Control Hosp Epidemiol 31:1298-300
Pogorzelska, Monika; Stone, Patricia W; Cohn, Elizabeth Gross et al. (2010) Changes in the institutional review board submission process for multicenter research over 6 years. Nurs Outlook 58:181-7
Kukafka, Rita; Millery, Mari; Chan, Connie et al. (2009) Assessing the need for an online decision-support tool to promote evidence-based practices of psychosocial counseling in HIV care. AIDS Care 21:103-8
Patel, Sameer J; Oshodi, Adebayo; Prasad, Priya et al. (2009) Antibiotic use in neonatal intensive care units and adherence with Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial Resistance. Pediatr Infect Dis J 28:1047-51
Stone, Patricia W; Dick, Andrew; Pogorzelska, Monika et al. (2009) Staffing and structure of infection prevention and control programs. Am J Infect Control 37:351-7
Bakken, Suzanne; Stone, Patricia W; Larson, Elaine L (2008) A nursing informatics research agenda for 2008-18: contextual influences and key components. Nurs Outlook 56:206-214.e3

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