This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Cell Biology and Bioimaging (CBB) Core (http://labs.pbrc.edu/cellbiology/index.htm) was organized in response to the specific needs of COBRE Project PIs and researchers at the Pennington Biomedical Research Center. Its purpose is to develop and provide state of the art bioimaging approaches to study the cell and molecular biology of biological processes in live and fixed cells and tissues, as well as physiological processes in vivo using micro CT. The CBB Core provides state of the art bioimaging and analytical instrumentation and support to facilitate data collection and analysis by COBRE Project PIs and PBRC faculty. The CBB Core is led by Dr David H Burk who serves as director and two research associates ?Ms Laura Roan and Ms Courtney Cain. Funding of the Pennington COBRE in September 2006 brought the Cell Biology and Bioimaging Core into existence and it was organized around five major analytical platforms: a Zeiss LSM-510 meta multiphoton confocal, an upright epifluorescence microscope and an inverted epifluorescence microscope, a scanning fluorometer for live cell imaging, and a FACS Caliber analytical cell sorter. A primary focus in the first two years was to enhance our existing microscopy expertise and development new expertise in the areas of flow cytometry, immunohistochemistry, imaging and image analysis. Our overall goal is to enhance the competitiveness of our faculty by providing seamless access to these technologies.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR021945-04
Application #
7959984
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2009-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
4
Fiscal Year
2009
Total Cost
$123,671
Indirect Cost
Name
Lsu Pennington Biomedical Research Center
Department
Type
Organized Research Units
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808
Stephens, Jacqueline M; Bailey, Jennifer L; Hang, Hardy et al. (2018) Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring) 26:1439-1447
Chang, Ji Suk; Ghosh, Sujoy; Newman, Susan et al. (2018) A map of the PGC-1?- and NT-PGC-1?-regulated transcriptional network in brown adipose tissue. Sci Rep 8:7876
Forney, Laura A; Stone, Kirsten P; Wanders, Desiree et al. (2018) The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. Appl Physiol Nutr Metab 43:123-130
Sarzynski, Mark A; Ruiz-Ramie, Jonathan J; Barber, Jacob L et al. (2018) Effects of Increasing Exercise Intensity and Dose on Multiple Measures of HDL (High-Density Lipoprotein) Function. Arterioscler Thromb Vasc Biol 38:943-952
Yu, Sangho; François, Marie; Huesing, Clara et al. (2018) The Hypothalamic Preoptic Area and Body Weight Control. Neuroendocrinology 106:187-194
Wanders, Desiree; Forney, Laura A; Stone, Kirsten P et al. (2018) The Components of Age-Dependent Effects of Dietary Methionine Restriction on Energy Balance in Rats. Obesity (Silver Spring) 26:740-746
François, Marie; Qualls-Creekmore, Emily; Berthoud, Hans-Rudolf et al. (2018) Genetics-based manipulation of adipose tissue sympathetic innervation. Physiol Behav 190:21-27
Kruger, Claudia; Burke, Susan J; Collier, J Jason et al. (2018) Lipid peroxidation regulates podocyte migration and cytoskeletal structure through redox sensitive RhoA signaling. Redox Biol 16:248-254
Yu, Sangho; Münzberg, Heike (2018) Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc 8:
Forney, Laura A; Stone, Kirsten P; Wanders, Desiree et al. (2018) Sensing and signaling mechanisms linking dietary methionine restriction to the behavioral and physiological components of the response. Front Neuroendocrinol 51:36-45

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