Innovative approaches to integrating biomedical and behavioral science are at the cutting edge of HIVprevention and treatment. To be effective, the most promising biomedical interventions will requirebehavioral expertise -- predicated on research that incorporates the social and community context. The valueof behavioral research is in turn leveraged by the integration of biological interventions and outcomes. TheSociobehavioral and Prevention Research Core (SPRC) facilitates such collaborations among social,behavioral and clinical scientists working on HIV at the UW. In its inaugural cycle, the SPRC was highlysuccessful in meeting its core aims of providing technical assistance, sponsoring public education events,publishing state-of-the-art reviews, and establishing new investigators in the areas of (1) preventionintervention studies, (2) clinical adherence research, and (3) modeling HIV transmission dynamics andpartnership networks. In addition, the core established five new institutional mechanisms for collaborativeresearch and practice. In this renewal we have refined our aims to focus on (1) HIV prevention researchsupport, and (2) community outreach for translation of research findings into practice. The new synergisticaims build on our original strengths, reflect our evolving direction, and extend our capacity in the emergingareas of biomedical prevention interventions and community-based participatory research. Specifically, thefirst aim of HIV prevention research support comprises the provision of technical assistance and organizationof forums for interdisciplinary research community development, with a new focus on expanding substantiveexpertise in substance use, mental health, and qualitative methods.
The second aim of supportingcommunity outreach involves working globally. Locally, we are proposing a new Community Outreachsubcore to facilitate collaboration with our Community Action Board and the Seattle/King County PublicHealth Department on community-based research priorities and translational opportunities. Internationally,we have formalized links to the International Core to identify collaborative research and translationalopportunities and established a new NIH-funded Center on HIV Prevention Research at the University ofNairobi.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI027757-21
Application #
7479037
Study Section
Special Emphasis Panel (ZAI1-EC-A (J1))
Project Start
2008-06-01
Project End
2013-05-31
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
21
Fiscal Year
2008
Total Cost
$171,426
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hamilton, Deven T; Goodreau, Steven M; Jenness, Samuel M et al. (2018) Potential Impact of HIV Preexposure Prophylaxis Among Black and White Adolescent Sexual Minority Males. Am J Public Health 108:S284-S291
Bilal, Usama; McCaul, Mary E; Crane, Heidi M et al. (2018) Predictors of Longitudinal Trajectories of Alcohol Consumption in People with HIV. Alcohol Clin Exp Res 42:561-570
Morgan, Ethan; Skaathun, Britt; Duvoisin, Rebeccah et al. (2018) Are HIV Seroconversions Among Young Men Who Have Sex With Men Associated With Social Network Proximity to Recently or Long-Term HIV-Infected Individuals? J Acquir Immune Defic Syndr 77:128-134
Wagner, Anjuli D; Njuguna, Irene N; Neary, Jillian et al. (2018) Financial Incentives to Increase Uptake of Pediatric HIV Testing (FIT): study protocol for a randomised controlled trial in Kenya. BMJ Open 8:e024310
Beima-Sofie, Kristin; Wamalwa, Dalton; Maleche-Obimbo, Elizabeth et al. (2018) Toll-like receptor 9 polymorphism is associated with increased Epstein-Barr virus and Cytomegalovirus acquisition in HIV-exposed infants. AIDS 32:267-270
Balkus, Jennifer E; Brown, Elizabeth R; Palanee-Phillips, Thesla et al. (2018) Performance of a Validated Risk Score to Predict HIV-1 Acquisition Among African Women Participating in a Trial of the Dapivirine Vaginal Ring. J Acquir Immune Defic Syndr 77:e8-e10
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786
Morgan, Ethan; Skaathun, Britt; Schneider, John A (2018) Sexual, Social, and Genetic Network Overlap: A Socio-Molecular Approach Toward Public Health Intervention of HIV. Am J Public Health 108:1528-1534
Fredericksen, R J; Gibbons, L; Brown, S et al. (2018) Medication understanding among patients living with multiple chronic conditions: Implications for patient-reported measures of adherence. Res Social Adm Pharm 14:540-544
Liu, Amy Y; De Rosa, Stephen C; Guthrie, Brandon L et al. (2018) High background in ELISpot assays is associated with elevated levels of immune activation in HIV-1-seronegative individuals in Nairobi. Immun Inflamm Dis 6:392-401

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