Abstract

The Skin Cell Culture Core (SCCC) aims to promote interdisciplinary research in skin cell biology among UAB campus-wide Skin Diseases Research Center (SDRC) members. The SCCC will provide expertise in the generation and maintenance of epidermal and dermal cell specific cultures from either mouse or human skin. In addition, it will provide expertise in the development of RAFT skin equivalent cultures.
The specific aims of the core are l) to provide a central source of epidermal and dermal cell types to Center members in an efficient cost effective manner, 2) to maintain quality control measures to ensure contamination-free cultures, 3) to provide expertise in specialized cell culture systems and transfection for both human and mouse cells and 4) to develop methods for generating mixed co-cultures of raft keratinocytes with Langerhans cells and/or melanocytes to anticipate increased interest and demand by SDRC members.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
5P30AR050948-04
Application #
7483157
Study Section
Special Emphasis Panel (ZAR1)
Project Start
2007-08-01
Project End
2009-07-31
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
4
Fiscal Year
2007
Total Cost
$105,914
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Frugé, Andrew D; Van der Pol, William; Rogers, Laura Q et al. (2018) Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial. J Acad Nutr Diet :
Frugé, Andrew D; Cases, Mallory G; Howell, Carrie R et al. (2018) Fingernail and toenail clippings as a non-invasive measure of chronic cortisol levels in adult cancer survivors. Cancer Causes Control 29:185-191
Stoll, Matthew L; Pierce, M Kathy; Watkins, Jordan A et al. (2018) Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis. Genes Immun :
Frugé, Andrew D; Ptacek, Travis; Tsuruta, Yuko et al. (2018) Dietary Changes Impact the Gut Microbe Composition in Overweight and Obese Men with Prostate Cancer Undergoing Radical Prostatectomy. J Acad Nutr Diet 118:714-723.e1
Koo, Hyunmin; Hakim, Joseph A; Powell, Mickie L et al. (2017) Metagenomics approach to the study of the gut microbiome structure and function in zebrafish Danio rerio fed with gluten formulated diet. J Microbiol Methods 135:69-76
Garcia, S S; Blackledge, M S; Michalek, S et al. (2017) Targeting of Streptococcus mutans Biofilms by a Novel Small Molecule Prevents Dental Caries and Preserves the Oral Microbiome. J Dent Res 96:807-814
Larson, Thomas R; Yother, Janet (2017) Streptococcus pneumoniae capsular polysaccharide is linked to peptidoglycan via a direct glycosidic bond to ?-D-N-acetylglucosamine. Proc Natl Acad Sci U S A 114:5695-5700
Brawner, K M; Kumar, R; Serrano, C A et al. (2017) Helicobacter pylori infection is associated with an altered gastric microbiota in children. Mucosal Immunol 10:1169-1177
Kim, T; Holleman, C L; Ptacek, T et al. (2017) Duodenal endoluminal barrier sleeve alters gut microbiota of ZDF rats. Int J Obes (Lond) 41:381-389
Sharma, Nirmal S; Wille, Keith M; Athira, S et al. (2017) Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients. J Heart Lung Transplant :

Showing the most recent 10 out of 228 publications