Abstract

The Electron Microscopy Core Facility provides readily accessible services to members of the University of Chicago Cancer Research Center for electron microscopic and cytochemical data collection. The facility provides immunocytochemistry and videoenhanced light microscope (VELM) services as well as electron microscopy. The EM Facility is equipped with both transmission and scanning electron microscopes with ancillary equipment suitable for all levels of microscopy. Full time technical assistance is available for consultation regarding projects, to prepare specimens from the time of fixation, to embedding, sectioning, microscopy and interpretation of photographs. The Facility provides special opportunities for immunolocalization of molecules either in frozen thin sections or Lowicryl-embedded samples. In collaboration with Dr. Robert Josephs, detailed analyses of individual molecules are available with a newly purchased Philips CM-120 electron microscope equipped with a cold transfer stage for viewing specimens at -170 degrees C. The VELM facility assists Cancer Center members to carry out qualitative and semi- quantitative analysis of the distribution of biological molecules within cells in normal, pathological and experimental conditions, using high resolution light microscopic cytochemistry.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014599-24
Application #
6236184
Study Section
Project Start
1997-09-01
Project End
1998-07-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
24
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
University of Chicago
Department
Type
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Zeineddine, Hussein A; Girard, Romuald; Saadat, Laleh et al. (2018) Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest :
Kane, Melissa; Deiss, Felicity; Chervonsky, Alexander et al. (2018) A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses. J Virol 92:
Xiao, Annie; Crosby, Jennie; Malin, Martha et al. (2018) Single-institution report of setup margins of voluntary deep-inspiration breath-hold (DIBH) whole breast radiotherapy implemented with real-time surface imaging. J Appl Clin Med Phys 19:205-213
Gamazon, Eric R; Trendowski, Matthew R; Wen, Yujia et al. (2018) Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma. Sci Rep 8:733
Girard, Romuald; Zeineddine, Hussein A; Koskimäki, Janne et al. (2018) Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth. Circ Res 122:1716-1721
Day, Kasey J; Casler, Jason C; Glick, Benjamin S (2018) Budding Yeast Has a Minimal Endomembrane System. Dev Cell 44:56-72.e4
Pu, Jinyue; Kentala, Kaitlin; Dickinson, Bryan C (2018) Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors. ACS Chem Biol 13:431-437
Pectasides, Eirini; Stachler, Matthew D; Derks, Sarah et al. (2018) Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov 8:37-48
Liu, Hongtao; Zha, Yuanyuan; Choudhury, Noura et al. (2018) WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia. Exp Hematol Oncol 7:1
Nageeb, Shaheen; Vu, Milkie; Malik, Sana et al. (2018) Adapting a religious health fatalism measure for use in Muslim populations. PLoS One 13:e0206898

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