Abstract

Current Use of Developmental Funds (03/01/06 - 02/28/07)New Investigator and Pilot ProjectsDuring Year 29 (03/01/06 - 02/28/07) of the current grant period, $504,650 (TDC) has been awarded to thefollowing investigators. With the addition of carryover funds from year 28, applications were solicited twice fordevelopmental funds (in January 2006 and again in June). Awards to Drs. Beere, Dyer, Gilbertson, Kitagawa,Lorsbach, Opferman, and Zakharenko were made in March 2006 and reports of their progress to date areincluded in this application (see below). Awards to Drs. Six, Haecker, and Williams were made in October2006; progress reports are not yet available for their research projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-30
Application #
7714832
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z (O1))
Project Start
2008-06-14
Project End
2013-02-28
Budget Start
2008-06-14
Budget End
2009-02-28
Support Year
30
Fiscal Year
2008
Total Cost
$79,702
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

van Oosterwijk, Jolieke G; Buelow, Daelynn R; Drenberg, Christina D et al. (2018) Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia. J Clin Invest 128:369-380
Howell, Carrie R; Wilson, Carmen L; Ehrhardt, Matthew J et al. (2018) Clinical impact of sedentary behaviors in adult survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort study. Cancer 124:1036-1043
Zamora, Anthony E; Crawford, Jeremy Chase; Thomas, Paul G (2018) Hitting the Target: How T Cells Detect and Eliminate Tumors. J Immunol 200:392-399
Zhong, Bo; Maharaj, Anil; Davis, Abigail et al. (2018) Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study. J Pharm Biomed Anal 156:97-103
Upadhyaya, Santhosh A; Robinson, Giles W; Harreld, Julie H et al. (2018) Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases. Childs Nerv Syst 34:605-610
Goldsby, Robert E; Stratton, Kayla L; Raber, Shannon et al. (2018) Long-term sequelae in survivors of childhood leukemia with Down syndrome: A childhood cancer survivor study report. Cancer 124:617-625
Howell, Carrie R; Krull, Kevin R; Partin, Robyn E et al. (2018) Randomized web-based physical activity intervention in adolescent survivors of childhood cancer. Pediatr Blood Cancer 65:e27216
Cherian, Milu T; Chai, Sergio C; Wright, William C et al. (2018) CINPA1 binds directly to constitutive androstane receptor and inhibits its activity. Biochem Pharmacol 152:211-223
Hoehn, Mary Ellen; Calderwood, Julie; Gannon, Edwin et al. (2018) Ocular complications in a young pediatric population following bone marrow transplantation. J AAPOS 22:102-106.e1
Devine, Katie A; Mertens, Ann C; Whitton, John A et al. (2018) Factors associated with physical activity among adolescent and young adult survivors of early childhood cancer: A report from the childhood cancer survivor study (CCSS). Psychooncology 27:613-619

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