Abstract

The Arizona Cancer Center Clinical Research Shared Service, directed by Thomas P. Miller, M.D., professor of medicine, has the overall mission of supporting and facilitating ACC clinical research initiatives for cancer treatment, prevention, screening, supportive care, and translational investigations. The shared services is organized into the following operational components: Clinical Trials Office (CTO), Clinical Data Management, Research Nursing, and the Arizona Cancer Center Clinical Research Information System Working Group. The Clinical Trials Office also assists the Arizona Cancer Center Scientific Review Committee (Protocol Review and Monitoring System). The benefits of centralization of clinical research services as detailed above include: availability of a mechanism for prioritization of studies and enforcement of peer review; improved internal and external awareness of protocols, programs, and treatment options available at the ACC; promotion of scientific communication and collaboration, standardization of research and resource management procedures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA023074-21
Application #
6269044
Study Section
Project Start
1998-08-14
Project End
1999-06-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
21
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Type
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Hsu, Chiu-Hsieh; Yu, Mandi (2018) Cox regression analysis with missing covariates via nonparametric multiple imputation. Stat Methods Med Res :962280218772592
Agasid, Mark T; Wang, Xuemin; Huang, Yiding et al. (2018) Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6.2 in mammalian cells. Protein Expr Purif 146:61-68
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Bell, Melanie L (2018) New guidance to improve sample size calculations for trials: eliciting the target difference. Trials 19:605
Lindeman, Leila R; Randtke, Edward A; High, Rachel A et al. (2018) A comparison of exogenous and endogenous CEST MRI methods for evaluating in vivo pH. Magn Reson Med 79:2766-2772
Remeniuk, Bethany; King, Tamara; Sukhtankar, Devki et al. (2018) Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain. Pain 159:684-698
Goldenberg, Joshua M; Pagel, Mark D; Cárdenas-Rodríguez, Julio (2018) Characterization of D-maltose as a T2 -exchange contrast agent for dynamic contrast-enhanced MRI. Magn Reson Med 80:1158-1164
Blohm-Mangone, Karen; Burkett, Nichole B; Tahsin, Shekha et al. (2018) Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV-Induced Skin Tumorigenesis in SKH-1 Mice. Cancer Prev Res (Phila) 11:265-278
Tao, Shasha; Rojo de la Vega, Montserrat; Chapman, Eli et al. (2018) The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer. Mol Carcinog 57:182-192
Russ, Atlantis; Hua, Anh B; Montfort, William R et al. (2018) Blocking ""don't eat me"" signal of CD47-SIRP? in hematological malignancies, an in-depth review. Blood Rev 32:480-489

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