The Diabetes Research Center has as its major research objectives multidisciplinary investigations of the pathogenesis of diabetes mellitus and its complications with the long-term goal of developing and evaluating new therapeutic approaches to these problems. The Diabetes Research Center program is designed (1) to facilitate and encourage the development of new interdisciplinary research programs and the involvement of established investigators not previously active in this field, (2) to assist the development of younger faculty members with primary training in diverse clinical and basic sciences who devote themselves to careers in diabetes mellitus related research, (3) to assist in the recruitment of new investigators to fill identified deficits in the overall research program, (4) to provide coordination of the planning and execution of the overall research program in diabetes, and of its related educational and research training programs, (5) to provide core support for the Diabetes Research Center research program through the provision of core facilities and services, (6) to provide an efficient mechanism for the development and evaluation of new research initiatives and support of pilot projects of high scientific merit, (7) to provide a means for evaluating the quality of the overall research program to insure its continued productivity, and (8) to provide a means for the dissemination of new information.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK019525-12
Application #
3101938
Study Section
(SRC)
Project Start
1977-03-01
Project End
1991-02-28
Budget Start
1988-03-01
Budget End
1989-02-28
Support Year
12
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Rickels, Michael R; Peleckis, Amy J; Dalton-Bakes, Cornelia et al. (2018) Continuous Glucose Monitoring for Hypoglycemia Avoidance and Glucose Counterregulation in Long-Standing Type 1 Diabetes. J Clin Endocrinol Metab 103:105-114
Guan, Dongyin; Xiong, Ying; Borck, Patricia C et al. (2018) Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell 174:831-842.e12
Jang, Cholsoon; Chen, Li; Rabinowitz, Joshua D (2018) Metabolomics and Isotope Tracing. Cell 173:822-837
Shoshkes-Carmel, Michal; Wang, Yue J; Wangensteen, Kirk J et al. (2018) Subepithelial telocytes are an important source of Wnts that supports intestinal crypts. Nature 557:242-246
Ibrahim, Fadia; Maragkakis, Manolis; Alexiou, Panagiotis et al. (2018) Ribothrypsis, a novel process of canonical mRNA decay, mediates ribosome-phased mRNA endonucleolysis. Nat Struct Mol Biol 25:302-310
Condon, David E; Tran, Phu V; Lien, Yu-Chin et al. (2018) Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus. BMC Bioinformatics 19:31
Cooney, Laura G; Milman, Lauren W; Hantsoo, Liisa et al. (2018) Cognitive-behavioral therapy improves weight loss and quality of life in women with polycystic ovary syndrome: a pilot randomized clinical trial. Fertil Steril 110:161-171.e1
Williams, Bianca; Correnti, Jason; Oranu, Amanke et al. (2018) A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis. FASEB J 32:130-142
Correnti, Jason M; Gottshall, Lauren; Lin, Annie et al. (2018) Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells. Sci Rep 8:12923
Qiu, Chengxiang; Huang, Shizheng; Park, Jihwan et al. (2018) Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease. Nat Med 24:1721-1731

Showing the most recent 10 out of 720 publications