Abstract

The objective of the Joslin Genomics Core Facility is to provide support to Joslin and a certain number of external investigators for analysis of gene expression, by providing equipment, expertise, and services in nucleic acid analysis that would be too specialized or costly for individual laboratories to perform independently. Core services include both high-density oligonucleotide array analysis, using the Affymetrix platform, and real-time quantitative fluorescent PCR analysis. The core also provides preliminary genomic analysis, software support, and technical advice regarding experimental design and sample preparation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK036836-23
Application #
7809551
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
23
Fiscal Year
2009
Total Cost
$191,088
Indirect Cost

  Institution

Name
Joslin Diabetes Center
Department
Type
DUNS #
071723084
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Stanford, Kristin I; Lynes, Matthew D; Takahashi, Hirokazu et al. (2018) 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake. Cell Metab 27:1357
Shah, Hetal S; Morieri, Mario Luca; Marcovina, Santica M et al. (2018) Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD. Diabetes Care 41:348-355
Mul, Joram D; Soto, Marion; Cahill, Michael E et al. (2018) Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ?FosB. Neuropsychopharmacology 43:1934-1942
Morieri, Mario Luca; Gao, He; Pigeyre, Marie et al. (2018) Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. Diabetes Care 41:2404-2413
Rezanejad, Habib; Ouziel-Yahalom, Limor; Keyzer, Charlotte A et al. (2018) Heterogeneity of SOX9 and HNF1? in Pancreatic Ducts Is Dynamic. Stem Cell Reports 10:725-738
Katz, Michelle L; Guo, Zijing; Cheema, Alina et al. (2018) Management of Cardiovascular Disease Risk in Teens with Type 1 Diabetes: Perspectives of Teens With and Without Dyslipidemia and Parents. Pediatr Diabetes :
Gordin, Daniel; Harjutsalo, Valma; Tinsley, Liane et al. (2018) Differential Association of Microvascular Attributions With Cardiovascular Disease in Patients With Long Duration of Type 1 Diabetes. Diabetes Care 41:815-822
Teló, G H; Dougher, C E; Volkening, L K et al. (2018) Predictors of changing insulin dose requirements and glycaemic control in children, adolescents and young adults with Type 1 diabetes. Diabet Med 35:1355-1363
Srinivasan, Shylaja; Kaur, Varinderpal; Chamarthi, Bindu et al. (2018) TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH). Diabetes Care 41:554-561
Goldford, Joshua E; Lu, Nanxi; Baji?, Djordje et al. (2018) Emergent simplicity in microbial community assembly. Science 361:469-474

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