Abstract

The DRTC Genomics Core unites the related resources and expertise of several unique genomics activities at UCSF. Although all of these activities already exist, by bringing them together the UCSF DRTC will enhance these activities, reduce duplication of effort, develop DRTC-specific resources, and increase access for DRTC members. Each facility has a full range of bioinformatics resources relevant to its particular technology. This Core works on the underlying principle that it will provide information, training, assistance and resources, but to get truly meaningful results, the individual investigators must be involved in each step of data production and analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
1P30DK063720-01
Application #
6612296
Study Section
Special Emphasis Panel (ZDK1-GRB-7 (O2))
Project Start
2002-09-01
Project End
2007-08-31
Budget Start
2002-09-01
Budget End
2004-01-31
Support Year
1
Fiscal Year
2003
Total Cost
$242,245
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Paulo, Esther; Wu, Dongmei; Wang, Yangmeng et al. (2018) Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. Sci Rep 8:11001
Miller, Corey N; Proekt, Irina; von Moltke, Jakob et al. (2018) Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature 559:627-631
Spence, Allyson; Purtha, Whitney; Tam, Janice et al. (2018) Revealing the specificity of regulatory T cells in murine autoimmune diabetes. Proc Natl Acad Sci U S A 115:5265-5270
Alba, Diana L; Farooq, Jeffrey A; Lin, Matthew Y C et al. (2018) Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans. J Clin Endocrinol Metab 103:3194-3204
Paruthiyil, Sreenivasan; Hagiwara, Shin-Ichiro; Kundassery, Keshav et al. (2018) Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice. Biol Sex Differ 9:49
Masand, Ruchi; Paulo, Esther; Wu, Dongmei et al. (2018) Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits. Cell Metab 27:616-629.e4
McQueen, Allison E; Koliwad, Suneil K; Wang, Jen-Chywan (2018) Fighting obesity by targeting factors regulating beige adipocytes. Curr Opin Clin Nutr Metab Care 21:437-443
Ali, Niwa; Zirak, Bahar; Truong, Hong-An et al. (2018) Skin-Resident T Cells Drive Dermal Dendritic Cell Migration in Response to Tissue Self-Antigen. J Immunol 200:3100-3108
Puri, Sapna; Roy, Nilotpal; Russ, Holger A et al. (2018) Replication confers ? cell immaturity. Nat Commun 9:485
Corbit, Kevin C; Camporez, João Paulo G; Edmunds, Lia R et al. (2018) Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes 67:208-221

Showing the most recent 10 out of 531 publications