Abstract

The goal of the Pulmonary Toxicology Facility Core (PTF, formerly the Inhalation Toxicology Facility) is to provide the facilities and expertise for EHSRC investigators to enhance the productivity and quality of their pulmonary toxicology research and to assist them in exploring new investigative areas in asthma, pulmonary biology, inhalation toxicology, or aerosol science. In addition, investigators from NIEHS-funded Environmental Health Centers are supported with expertise and assays for evaluation of exposures to asthma triggers. This facility provides assistance for testing hypotheses regarding the: ? Pulmonary biology of asthma and other environmental lung diseases; ? Development and prevention of environmental lung disease; ? Physicochemical properties and behavior of endotoxin, allergens, bioaerosols, and other airborne toxicants;and ? Performance of sampling devices commonly used by aerosol scientists and hygienists for environmental assessment.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES005605-19
Application #
7798181
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
19
Fiscal Year
2009
Total Cost
$262,796
Indirect Cost

  Institution

Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Liu, Ling; Urch, Bruce; Szyszkowicz, Mieczyslaw et al. (2018) Metals and oxidative potential in urban particulate matter influence systemic inflammatory and neural biomarkers: A controlled exposure study. Environ Int 121:1331-1340
Lehmler, Hans-Joachim; Gadogbe, Manuel; Liu, Buyun et al. (2018) Environmental tin exposure in a nationally representative sample of U.S. adults and children: The National Health and Nutrition Examination Survey 2011-2014. Environ Pollut 240:599-606
Gilbert, Paul A; Laroche, Helena H; Wallace, Robert B et al. (2018) Extending Work on Rural Health Disparities: A Commentary on Matthews and Colleagues' Report. J Rural Health 34:119-121
Li, Xueshu; Holland, Erika B; Feng, Wei et al. (2018) Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int 25:16508-16521
Stapleton, Emma M; O'Shaughnessy, Patrick T; Locke, Sarah J et al. (2018) A task-based analysis of black carbon exposure in Iowa farmers during harvest. J Occup Environ Hyg 15:293-304
Andreotti, Gabriella; Koutros, Stella; Hofmann, Jonathan N et al. (2018) Glyphosate Use and Cancer Incidence in the Agricultural Health Study. J Natl Cancer Inst 110:509-516
P?n?íková, Kate?ina; Svržková, Lucie; Strapá?ová, Simona et al. (2018) In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environ Pollut 237:473-486
Schoenfeld, Joshua D; Sibenaller, Zita A; Mapuskar, Kranti A et al. (2018) Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models. Redox Biol 14:417-422
Martinez, Carlos H; Li, Sara X; Hirzel, Andrew J et al. (2018) Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. J Allergy Clin Immunol 141:429-432
Brandt, Kristin E; Falls, Kelly C; Schoenfeld, Joshua D et al. (2018) Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol 14:82-87

Showing the most recent 10 out of 1123 publications