PILOT PROJECTS : ABSTRACT The Pilot Project Program is a key-component of the Center of Excellence in Environmental Toxicology (CEET) that builds capacity in environmental health sciences (EHS). The Pilot Project Program serves to support Early- Stage Investigators (ESI) that are interested in pursuing EHS, and senior investigators who may be embarking on EHS projects for the first-time. To assist in the pilot project application process, we run a grants-writing program within the Career Development activities of the Administrative Core. The Pilot Projects available fall into four categories: (a) Mentored Scientist Transition Award (MSTA) which is our primary mechanism of funding a ESI (new recruits, clinician scientists, research track faculty) who need protected time through salary and research support to establish their independent research programs; (b) an Opportunity Award open to all junior and senior faculty who propose an innovative EHS project which is not ready for federal funding; (c) a ?Rapid Response? award to promote community engaged research or provide funds to a faculty member who urgently needs to generate preliminary data for a EHS relevant grant application; and (d) Focus Research Awards to support research in the thematic areas of the Center: Air pollution & Lung Health, Environmental Exposures & Cancer, Windows-of-Susceptibility and Environmental Neuroscience with emphasis to support multi-investigator grant applications. Applications receive high priority if they are likely to lead to extramural funding from NIEHS or respond to a RFA on which NIEHS is a sponsor; and if they use one or more facility cores, the Integrative Health Sciences Facility Core (IHSFC), the Translational Biomarker Core (TBC) and Exposure Biology Informatics Core (EBIC). Pilot project awardees are invited back after 12 months of funding to present on their progress in the CEET seminar series. Outcome metrics such as grant applications submitted, grants awarded, and publications are updated on an annual basis to account for the significant lag-phase that can exist between the pilot project award and these successful outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES013508-15
Application #
9917972
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
15
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Mishra, Om P; Popov, Anatoliy V; Pietrofesa, Ralph A et al. (2018) Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochim Biophys Acta Gen Subj 1862:1364-1375
Hwang, Michael T; Wang, Zejun; Ping, Jinglei et al. (2018) DNA Nanotweezers and Graphene Transistor Enable Label-Free Genotyping. Adv Mater :e1802440
Lochbuehler, Kirsten; Wileyto, E Paul; Tang, Kathy Z et al. (2018) Do current and former cigarette smokers have an attentional bias for e-cigarette cues? J Psychopharmacol 32:316-323
SanMiguel, Jennifer M; Abramowitz, Lara K; Bartolomei, Marisa S (2018) Imprinted gene dysregulation in a Tet1 null mouse model is stochastic and variable in the germline and offspring. Development 145:
Nyenhuis, Sharmilee M; Apter, Andrea J; Schatz, Michael et al. (2018) Comparative effectiveness trials in asthma - how will I recognize one? Curr Opin Pulm Med 24:78-82
Kuda, Ondrej; Brezinova, Marie; Silhavy, Jan et al. (2018) Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid. Diabetes 67:1190-1199
Manduchi, Elisabetta; Chesi, Alessandra; Hall, Molly A et al. (2018) Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS. Pac Symp Biocomput 23:548-558
Raefsky, Sophia M; Furman, Ran; Milne, Ginger et al. (2018) Deuterated polyunsaturated fatty acids reduce brain lipid peroxidation and hippocampal amyloid ?-peptide levels, without discernable behavioral effects in an APP/PS1 mutant transgenic mouse model of Alzheimer's disease. Neurobiol Aging 66:165-176
Rockstrom, Matthew D; Chen, Liangyu; Taishi, Ping et al. (2018) Tumor necrosis factor alpha in sleep regulation. Sleep Med Rev 40:69-78
Portnoy, Jill; Raine, Adrian; Liu, Jianghong et al. (2018) Reductions of intimate partner violence resulting from supplementing children with omega-3 fatty acids: A randomized, double-blind, placebo-controlled, stratified, parallel-group trial. Aggress Behav :

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