The goal of the Research Methods Core (RMC) will be to develop, enhance, and provide state-of-the-art, sophisticated methodological expertise to the investigators in the Center conducting studies of interventions and services research related to the care of community-dwelling middle-aged and elderly people with schizophrenia and other psychotic disorders. This work will involve active collaboration with methodologists from diverse academic backgrounds within and outside of health sciences such as biostatistics, epidemiology, preventive, medicine, medical anthropology, engineering, computer science, behavioral and social science, among others. The Core will include six specialized but interacting Units: The goal of the Research Methods Core (RMC) will be to develop, enhance, and provide state-of-the-art, sophisticated methodological expertise to the investigators in the Center conducting studies of interventions and services research related to the care of community-dwelling middle-aged and elderly people with schizophrenia and other psychotic disorders. This work will involve active collaboration with methodologists from diverse academic backgrounds within and outside of health sciences such as biostatistics, epidemiology, preventive medicine, medicinal anthropology, engineering, computer science, behavioral and social science, among others. The Core will include six specialized but interacting Units: I. Unit on Instruments for Patient Assessment-The Unit will study development for instruments for assessing patients' cognitive deficits, everyday functioning, quality of life, motor and psychomotor dysfunction, and medication adherence that are useful for research as well as clinical purposes in community practice. II. Unit on Integrating Qualitative and Quantitative Methods for Assessing Unmet Healthcare Needs. III. Unit on Studies of Ethnic Minority Subjects-The initial focus of this Unit will be on Latino (especially Mexican American) patients. IV. Methodology, Biostatistics and Data Management Unit?This Unit will work on developing and utilizing novel techniques such as adaptive clinical trials, speculative research, and new model building and testing as well as use of wireless communication technologies for access to date from remote sources. V. Bioethics Unit-The Bioethics Unit will seek to develop research methods for assessing and enhancing decisional capacity, and VI. Unit on Dissemination and Health Systems Change. Each unit is headed by a senior investigator who is a leader in the respective field, but also includes a mix of senior and junior co-investigators. The Units will have research, service, and training functions. It is our vision that the RMC will develop and evaluate innovative research methods, many of which will eventually become standard ones and get incorporated into the routine methods employed in clinical or research settings.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
1P30MH066248-01
Application #
6684403
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2002-09-20
Project End
2007-06-30
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Dev, Sheena I; Moore, Raeanne C; Soontornniyomkij, Benchawanna et al. (2017) Peripheral inflammation related to lower fMRI activation during a working memory task and resting functional connectivity among older adults: a preliminary study. Int J Geriatr Psychiatry 32:341-349
Moore, Raeanne C; Harmell, Alexandrea L; Harvey, Philip D et al. (2015) Improving the understanding of the link between cognition and functional capacity in schizophrenia and bipolar disorder. Schizophr Res 169:121-127
Martin, Averria Sirkin; Palmer, Barton W; Rock, David et al. (2015) Associations of self-perceived successful aging in young-old versus old-old adults. Int Psychogeriatr 27:601-9
Ng, Rowena; Fish, Scott; Granholm, Eric (2015) Insight and theory of mind in schizophrenia. Psychiatry Res 225:169-174
Moore, Raeanne C; Dev, Sheena I; Jeste, Dilip V et al. (2015) Distinct neural correlates of emotional and cognitive empathy in older adults. Psychiatry Res 232:42-50
Moore, Raeanne C; Martin, A'verria Sirkin; Kaup, Allison R et al. (2015) From suffering to caring: a model of differences among older adults in levels of compassion. Int J Geriatr Psychiatry 30:185-91
Martin, A'verria Sirkin; Distelberg, Brian; Palmer, Barton W et al. (2015) Development of a new multidimensional individual and interpersonal resilience measure for older adults. Aging Ment Health 19:32-45
Moore, Raeanne C; Eyler, Lisa T; Mausbach, Brent T et al. (2015) Complex interplay between health and successful aging: role of perceived stress, resilience, and social support. Am J Geriatr Psychiatry 23:622-32
Lee, Aaron A; McKibbin, Christine L; Bourassa, Katelynn A et al. (2014) Depression, diabetic complications and disability among persons with comorbid schizophrenia and type 2 diabetes. Psychosomatics 55:343-351
Harmell, Alexandrea L; Mausbach, Brent T; Moore, Raeanne C et al. (2014) Longitudinal study of sustained attention in outpatients with bipolar disorder. J Int Neuropsychol Soc 20:230-7

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