The purpose of the proposal is to study the acute and chronic effects of alcohol upon the microcirculation. Cardiac, renal, cerebral and pulmonary tissue will be obtained from hamster pups and placed in a special chamber in the cheek pouch of a recipient hamster. Subsequently, the microcirculation of these tissues can be characterized in terms of their reactivity and permeability when exposed to alcohol acutely and chronically. The study will provide unique information regarding the effect of alcohol on the living microcirculation.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA006825-03
Application #
3110207
Study Section
Alcohol Biomedical Research Review Committee (ALCB)
Project Start
1986-04-01
Project End
1989-06-30
Budget Start
1988-04-01
Budget End
1989-06-30
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198