Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA009005-05
Application #
2045038
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1991-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Bhave, Sanjiv V; Hoffman, Paula L (2004) Phosphatidylinositol 3'-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol. J Neurochem 88:359-69
Wu, P H; Tabakoff, B; Szabo, G et al. (2001) Chronic ethanol exposure results in increased acute functional tolerance in selected lines of HAFT and LAFT mice. Psychopharmacology (Berl) 155:405-12
Snell, L D; Bhave, S V; Tabakoff, B et al. (2001) Chronic ethanol exposure delays the 'developmental switch' of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons. J Neurochem 78:396-405
Tabakoff, B; Nelson, E; Yoshimura, M et al. (2001) Phosphorylation cascades control the actions of ethanol on cell cAMP signalling. J Biomed Sci 8:44-51
Bhave, S V; Snell, L D; Tabakoff, B et al. (2000) Chronic ethanol exposure attenuates the anti-apoptotic effect of NMDA in cerebellar granule neurons. J Neurochem 75:1035-44
Bhave, S V; Snell, L D; Tabakoff, B et al. (1999) Ethanol sensitivity of NMDA receptor function in developing cerebellar granule neurons. Eur J Pharmacol 369:247-59
Bhave, S V; Ghoda, L; Hoffman, P L (1999) Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action. J Neurosci 19:3277-86
Valenzuela, C F; Bhave, S; Hoffman, P et al. (1998) Acute effects of ethanol on pharmacologically isolated kainate receptors in cerebellar granule neurons: comparison with NMDA and AMPA receptors. J Neurochem 71:1777-80
Bhave, S V; Hoffman, P L (1997) Ethanol promotes apoptosis in cerebellar granule cells by inhibiting the trophic effect of NMDA. J Neurochem 68:578-86
Bhave, S V; Snell, L D; Tabakoff, B et al. (1996) Mechanism of ethanol inhibition of NMDA receptor function in primary cultures of cerebral cortical cells. Alcohol Clin Exp Res 20:934-41

Showing the most recent 10 out of 24 publications