Central Mechanisms of Ethanol Discrimination

Hodge, Clyde W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• Type: Research Project (R01)
• Project #: 5R01AA009981-03
• Application #: 2000343
• Study Section: Special Emphasis Panel (SRCA (51))
• Project Start: 1995-01-01
• Project End: 1997-01-31
• Budget Start: 1997-01-01
• Budget End: 1997-01-31
• Support Year: 3
• Fiscal Year: 1997

Institution

• Name: Wake Forest University Health Sciences
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 041418799
• City: Winston-Salem
• State: NC
• Country: United States
• Zip Code: 27106

Publications

Besheer, Joyce; Hodge, Clyde W (2005) Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol. Neuropsychopharmacology 30:747-57

Schroeder, Jason P; Overstreet, David H; Hodge, Clyde W (2005) The neuropeptide-Y Y5 receptor antagonist L-152,804 decreases alcohol self-administration in inbred alcohol-preferring (iP) rats. Alcohol 36:179-86

Besheer, Joyce; Lepoutre, Veronique; Hodge, Clyde W (2004) GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice. Psychopharmacology (Berl) 174:358-66

Hodge, Clyde W; Kelley, Stephen P; Bratt, Alison M et al. (2004) 5-HT(3A) receptor subunit is required for 5-HT3 antagonist-induced reductions in alcohol drinking. Neuropsychopharmacology 29:1807-13

Camarini, Rosana; Hodge, Clyde W (2004) Ethanol preexposure increases ethanol self-administration in C57BL/6J and DBA/2J mice. Pharmacol Biochem Behav 79:623-32

Kelley, Stephen P; Hodge, Clyde W (2003) The 5-HT3 antagonist Y-25130 blocks cocaine-induced lowering of ICSS reward thresholds in the rat. Pharmacol Biochem Behav 74:297-302

Schroeder, Jason P; Olive, Foster; Koenig, Heather et al. (2003) Intra-amygdala infusion of the NPY Y1 receptor antagonist BIBP 3226 attenuates operant ethanol self-administration. Alcohol Clin Exp Res 27:1884-91

Besheer, Joyce; Cox, Amy A; Hodge, Clyde W (2003) Coregulation of ethanol discrimination by the nucleus accumbens and amygdala. Alcohol Clin Exp Res 27:450-6

Schroeder, Jason P; Iller, Kimberly A; Hodge, Clyde W (2003) Neuropeptide-Y Y5 receptors modulate the onset and maintenance of operant ethanol self-administration. Alcohol Clin Exp Res 27:1912-20

Hodge, Clyde W; Raber, Jacob; McMahon, Thomas et al. (2002) Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon. J Clin Invest 110:1003-10