Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA010025-01A2
Application #
2046448
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1996-04-01
Project End
2001-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Psychology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Criswell, Hugh E; Ming, Zhen; Kelm, M Katherine et al. (2008) Brain regional differences in the effect of ethanol on GABA release from presynaptic terminals. J Pharmacol Exp Ther 326:596-603
Knapp, Darin J; Overstreet, David H; Moy, Sheryl S et al. (2004) SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats. Alcohol 32:101-11
Criswell, Hugh E; Ming, Zhen; Griffith, Benjamin L et al. (2003) Comparison of effect of ethanol on N-methyl-D-aspartate- and GABA-gated currents from acutely dissociated neurons: absence of regional differences in sensitivity to ethanol. J Pharmacol Exp Ther 304:192-9
Ming, Zhen; Griffith, Benjamin L; Breese, George R et al. (2002) Changes in the effect of isoflurane on N-methyl-D-aspartic acid-gated currents in cultured cerebral cortical neurons with time in culture: evidence for subunit specificity. Anesthesiology 97:856-67
Haberman, Rebecca; Criswell, Hugh; Snowdy, Stephen et al. (2002) Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity. Mol Ther 6:495-500
Ming, Z; Knapp, D J; Mueller, R A et al. (2001) Differential modulation of GABA- and NMDA-gated currents by ethanol and isoflurane in cultured rat cerebral cortical neurons. Brain Res 920:117-24
Yang, X; Criswell, H E; Breese, G R (2000) Ethanol modulation of gamma-aminobutyric acid (GABA)-mediated inhibition of cerebellar Purkinje neurons: relationship to GABAb receptor input. Alcohol Clin Exp Res 24:682-90
Criswell, H E; McCown, T J; Ming, Z et al. (1999) Interactive role for neurosteroids in ethanol enhancement of gamma-aminobutyric acid-gated currents from dissociated substantia nigra reticulata neurons. J Pharmacol Exp Ther 291:1054-9
Yang, X; Knapp, D J; Criswell, H E et al. (1998) Action of ethanol and zolpidem on gamma-aminobutyric acid responses from cerebellar Purkinje neurons: relationship to beta-adrenergic receptor input. Alcohol Clin Exp Res 22:1655-61
Duncan, G E; Moy, S S; Knapp, D J et al. (1998) Metabolic mapping of the rat brain after subanesthetic doses of ketamine: potential relevance to schizophrenia. Brain Res 787:181-90

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