Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
7R01AA010102-03
Application #
2682981
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1998-02-01
Project End
2000-03-31
Budget Start
1998-02-01
Budget End
1998-03-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
de la Monte, Suzanne M; Wands, Jack R (2002) The AD7c-ntp neuronal thread protein biomarker for detecting Alzheimer's disease. Front Biosci 7:d989-96
de la Monte, S M; Wands, J R (2001) Alzheimer-associated neuronal thread protein-induced apoptosis and impaired mitochondrial function in human central nervous system-derived neuronal cells. J Neuropathol Exp Neurol 60:195-207
de la Monte, S M; Wands, J R (2001) Neurodegeneration changes in primary central nervous system neurons transfected with the Alzheimer-associated neuronal thread protein gene. Cell Mol Life Sci 58:844-9
de la Monte, S M; Neely, T R; Cannon, J et al. (2000) Oxidative stress and hypoxia-like injury cause Alzheimer-type molecular abnormalities in central nervous system neurons. Cell Mol Life Sci 57:1471-81
de la Monte, S M; Ganju, N; Wands, J R (1999) Microtiter immunocytochemical ELISA assay. Biotechniques 26:1073-6, 1078
de la Monte, S M; Ganju, N; Tanaka, S et al. (1999) Differential effects of ethanol on insulin-signaling through the insulin receptor substrate-1. Alcohol Clin Exp Res 23:770-7
Banerjee, K; Mohr, L; Wands, J R et al. (1998) Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells. Alcohol Clin Exp Res 22:2093-101
Chiche, J D; Schlutsmeyer, S M; Bloch, D B et al. (1998) Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 273:34263-71
Mohr, L; Tanaka, S; Wands, J R (1998) Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice. Gastroenterology 115:1558-65