Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA011393-01
Application #
2047721
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1996-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Newton, Gerald L; Fahey, Robert C (2002) Mycothiol biochemistry. Arch Microbiol 178:388-94
Newton, G L; Av-Gay, Y; Fahey, R C (2000) N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis. J Bacteriol 182:6958-63
Newton, G L; Av-Gay, Y; Fahey, R C (2000) A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase. Biochemistry 39:10739-46
Unson, M D; Newton, G L; Arnold, K F et al. (1999) Improved methods for immunoassay of mycothiol. J Clin Microbiol 37:2153-7
Newton, G L; Unson, M D; Anderberg, S J et al. (1999) Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis. Biochem Biophys Res Commun 255:239-44
Anderberg, S J; Newton, G L; Fahey, R C (1998) Mycothiol biosynthesis and metabolism. Cellular levels of potential intermediates in the biosynthesis and degradation of mycothiol in mycobacterium smegmatis. J Biol Chem 273:30391-7
Unson, M D; Newton, G L; Davis, C et al. (1998) An immunoassay for the detection and quantitative determination of mycothiol. J Immunol Methods 214:29-39