Alcohol has emerged as a critical cofactor in HIV infection. Yet we still lack an understanding of how in-the-moment forces - such as acute intoxication - affect a person's decision to engage in risky behaviors. Our long-term goal is to illuminate the role played by intoxication in decision-making related to infectious diseases. Perhaps there exist heretofore-uninvestigated biphasic effects that would clarify paradoxical evidence of alcohol-induced suppression and associated outcomes. Such consideration may expand our understanding of alcohol and risky outcomes.
The specific aims are (1) to examine the linkages among alcohol and risky behavior; (2) to evaluate the viability of the alcohol myopia model for explaining postdrinking attitudes and behavior; (3) to investigate alcohol impairment of behavior control; and (4) to expand the currently scant fund of experimental data about women after drinking by evaluating for systematic gender differences in these relationships for intoxication and risky behavior. To address these aims, six controlled laboratory experiments are planned systematically manipulating alcohol (alcohol, none), BAC limb (ascending, descending), dosage (moderate, high), behavioral activation (maximize, none, suppress), and conflict (high, low). The sample will be elevated-risk, unmarried men and women attending urban university campuses and/or residing in urban census tracts. The overarching hypothesis is that alcohol impairs the capacity to inhibit behavior and that it directly and indirectly (through its impairment of inhibition) impairs the capacity to inhibit risk-taking. Alcohol should interact with limb such that ascending exceeds descending impact and should interact such that alcohol fosters riskier outcomes under high conflict. In concert with personality and other factors, the data may inform key knowledge gaps, advance theory, and foster refinement of existing prevention approaches and formulation of new ones.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA013565-02
Application #
6533716
Study Section
Special Emphasis Panel (ZAA1-CC (24))
Program Officer
Freeman, Robert
Project Start
2001-09-26
Project End
2006-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
2
Fiscal Year
2002
Total Cost
$379,000
Indirect Cost
Name
University of Washington
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
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Bird, Elizabeth R; Gilmore, Amanda K; Stappenbeck, Cynthia A et al. (2017) Women's Sex-Related Dissociation: The Effects of Alcohol Intoxication, Attentional Control Instructions, and History of Childhood Sexual Abuse. J Sex Marital Ther 43:121-131
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Staples, Jennifer M; George, William H; Stappenbeck, Cynthia A et al. (2015) Alcohol myopia and sexual abdication among women: examining the moderating effect of child sexual abuse. Addict Behav 41:72-7
Gilmore, Amanda K; Schacht, Rebecca L; George, William H et al. (2014) Verbal Sexual Coercion Experiences, Sexual Risk, and Substance Use in Women. J Aggress Maltreat Trauma 23:725-739
Gilmore, Amanda K; George, William H; Nguyen, Hong V et al. (2013) Influences of situational factors and alcohol expectancies on sexual desire and arousal among heavy-episodic drinking women: acute alcohol intoxication and condom availability. Arch Sex Behav 42:949-59
Koo, Kelly H; Stephens, Kari A; Lindgren, Kristen P et al. (2012) Misogyny, acculturation, and ethnic identity: relation to rape-supportive attitudes in Asian American college men. Arch Sex Behav 41:1005-14
Nguyen, Hong V; Koo, Kelly H; Davis, Kelly Cue et al. (2012) Risky sex: interactions among ethnicity, sexual sensation seeking, sexual inhibition, and sexual excitation. Arch Sex Behav 41:1231-9
George, William H; Davis, Kelly Cue; Heiman, Julia R et al. (2011) Women's sexual arousal: effects of high alcohol dosages and self-control instructions. Horm Behav 59:730-8
Schacht, Rebecca L; Stoner, Susan A; George, William H et al. (2010) Idiographically determined versus standard absorption periods in alcohol administration studies. Alcohol Clin Exp Res 34:925-7

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