Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
2R01AG002224-17
Application #
2048690
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1980-04-01
Project End
2000-06-30
Budget Start
1996-07-11
Budget End
1997-06-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Physiology
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Moran, Francisco M; Chen, Jiangang; Gee, Nancy A et al. (2013) Dehydroepiandrosterone sulfate levels reflect endogenous luteinizing hormone production and response to human chorionic gonadotropin challenge in older female macaque (Macaca fascicularis). Menopause 20:329-35
Brown, Candice M; Becker, Jessica O; Wise, Phyllis M et al. (2011) Simultaneous determination of 6 L-arginine metabolites in human and mouse plasma by using hydrophilic-interaction chromatography and electrospray tandem mass spectrometry. Clin Chem 57:701-9
Harrison, F E; May, J M; McDonald, M P (2010) Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice. Pharmacol Biochem Behav 94:543-52
Brown, Candice M; Mulcahey, Tara A; Filipek, Nicole C et al. (2010) Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors alpha and beta. Endocrinology 151:4916-25
Suzuki, Shotaro; Brown, Candice M; Wise, Phyllis M (2009) Neuroprotective effects of estrogens following ischemic stroke. Front Neuroendocrinol 30:201-11
Downs, Jodi L; Wise, Phyllis M (2009) The role of the brain in female reproductive aging. Mol Cell Endocrinol 299:32-8
Wise, Phyllis M; Suzuki, Shotaro; Brown, Candice M (2009) Estradiol: a hormone with diverse and contradictory neuroprotective actions. Dialogues Clin Neurosci 11:297-303
Brown, Candice M; Suzuki, Shotaro; Jelks, Karen A B et al. (2009) Estradiol is a potent protective, restorative, and trophic factor after brain injury. Semin Reprod Med 27:240-9
Brown, Candice M; Dela Cruz, Christopher D; Yang, Enhua et al. (2008) Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury. Exp Neurol 210:782-7
Jelks, Karen Bozak; Wylie, Rebecca; Floyd, Candace L et al. (2007) Estradiol targets synaptic proteins to induce glutamatergic synapse formation in cultured hippocampal neurons: critical role of estrogen receptor-alpha. J Neurosci 27:6903-13

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