Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG008201-02
Application #
3119691
Study Section
Aging Review Committee (AGE)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1989-08-01
Budget End
1990-07-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Samuel, W; Alford, M; Hofstetter, C R et al. (1997) Dementia with Lewy bodies versus pure Alzheimer disease: differences in cognition, neuropathology, cholinergic dysfunction, and synapse density. J Neuropathol Exp Neurol 56:499-508
Hansen, L A; Samuel, W (1997) Criteria for Alzheimer's disease and the nosology of dementia with Lewy bodies. Neurology 48:126-32
Samuel, W; Masliah, E; Brush, D E et al. (1997) Lesions in the dentate hilum and CA2/CA3 regions of the rat hippocampus produce cognitive deficits that correlate with site-specific glial activation. Neurobiol Learn Mem 68:103-16
Samuel, W; Galasko, D; Masliah, E et al. (1996) Neocortical lewy body counts correlate with dementia in the Lewy body variant of Alzheimer's disease. J Neuropathol Exp Neurol 55:44-52
Godson, C; Masliah, E; Balboa, M A et al. (1996) Isoform-specific redistribution of protein kinase C in living cells. Biochim Biophys Acta 1313:63-71
Terry, R D (1994) Neuropathological changes in Alzheimer disease. Prog Brain Res 101:383-90
Masliah, E; Honer, W G; Mallory, M et al. (1994) Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus. Acta Neuropathol 87:135-42
Nagra, R M; Masliah, E; Burrola, P G et al. (1994) Neocortical pathology in chronic murine retroviral encephalitis. J Neuropathol Exp Neurol 53:572-81
Alford, M F; Masliah, E; Hansen, L A et al. (1994) A simple dot-immunobinding assay for quantification of synaptophysin-like immunoreactivity in human brain. J Histochem Cytochem 42:283-7
Hansen, L A; Galasko, D; Samuel, W et al. (1994) Apolipoprotein-E epsilon-4 is associated with increased neurofibrillary pathology in the Lewy body variant of Alzheimer's disease. Neurosci Lett 182:63-5

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