Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG008708-01
Application #
3120439
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1989-12-01
Project End
1994-11-30
Budget Start
1989-12-01
Budget End
1990-11-30
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Type
Schools of Medicine
DUNS #
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Saito, H; Papaconstantinou, J; Sato, H et al. (1997) Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence. J Biol Chem 272:8157-60
Grigoriev, V G; Thweatt, R; Moerman, E J et al. (1996) Expression of senescence-induced protein WS3-10 in vivo and in vitro. Exp Gerontol 31:145-57
Wang, S; Moerman, E J; Jones, R A et al. (1996) Characterization of IGFBP-3, PAI-1 and SPARC mRNA expression in senescent fibroblasts. Mech Ageing Dev 92:121-32
Lecka-Czernik, B; Moerman, E J; Jones, R A et al. (1996) Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts. Exp Gerontol 31:159-74
Grigoriev, V G; Moerman, E J; Goldstein, S (1995) Overexpression of insulin-like growth factor binding protein-3 by senescent human fibroblasts: attenuation of the mitogenic response to IGF-I. Exp Cell Res 219:315-21
Rasoamanantena, P; Thweatt, R; Labat-Robert, J et al. (1994) Altered regulation of fibronectin gene expression in Werner syndrome fibroblasts. Exp Cell Res 213:121-7
Goldstein, S; Liu, S; Lumpkin Jr, C K et al. (1994) Derangements in calcium-dependent membrane currents in senescent human fibroblasts are associated with overexpression of a novel gene sequence. Ann N Y Acad Sci 747:302-12
Goldstein, S; Moerman, E J; Fujii, S et al. (1994) Overexpression of plasminogen activator inhibitor type-1 in senescent fibroblasts from normal subjects and those with Werner syndrome. J Cell Physiol 161:571-9
Grigoriev, V G; Moerman, E J; Goldstein, S (1994) Senescence and cell density of human diploid fibroblasts influence metabolism of insulin-like growth factor binding proteins. J Cell Physiol 160:203-11
Liu, S; Thweatt, R; Lumpkin Jr, C K et al. (1994) Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein. Proc Natl Acad Sci U S A 91:2186-90

Showing the most recent 10 out of 22 publications