Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
2R01AG011386-04A1
Application #
2052579
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1992-09-01
Project End
2001-08-31
Budget Start
1996-09-15
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Neurology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Judge, Susan I V; Yeh, Jay Z; Goolsby, James E et al. (2002) Determinants of 4-aminopyridine sensitivity in a human brain kv1.4 k(+) channel: phenylalanine substitutions in leucine heptad repeat region stabilize channel closed state. Mol Pharmacol 61:913-20
Mah, A L; Perry, G; Smith, M A et al. (2000) Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol 151:847-62
Janicki, S M; Monteiro, M J (1999) Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant. Am J Pathol 155:135-44
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Stabler, S M; Ostrowski, L L; Janicki, S M et al. (1999) A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein. J Cell Biol 145:1277-92
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Starr, R; Hall, F L; Monteiro, M J (1996) A cdc2-like kinase distinct from cdk5 is associated with neurofilaments. J Cell Sci 109 ( Pt 6):1565-73
Xiao, J; Perry, G; Troncoso, J et al. (1996) alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease. J Neuropathol Exp Neurol 55:954-63
Starr, R; Attema, B; DeVries, G H et al. (1996) Neurofilament phosphorylation is modulated by myelination. J Neurosci Res 44:328-37
Hsu, C; Janicki, S; Monteiro, M J (1995) The first intron of the mouse neurofilament light gene (NF-L) increases gene expression. Brain Res Mol Brain Res 32:241-51

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