Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG011465-03
Application #
2052647
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Program Officer
Finkelstein, David B
Project Start
1993-12-01
Project End
1998-11-30
Budget Start
1995-12-20
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Pharmacology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Kim, Yong-Woon; Scarpace, Philip J (2003) Repeated fasting/refeeding elevates plasma leptin without increasing fat mass in rats. Physiol Behav 78:459-64
Scarpace, P J; Matheny, M; Tumer, N (2001) Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats. Neuroscience 104:1111-7
Scarpace, P J; Tumer, N (2001) Peripheral and hypothalamic leptin resistance with age-related obesity. Physiol Behav 74:721-7
Scarpace, P J; Matheny, M; Moore, R L et al. (2000) Impaired leptin responsiveness in aged rats. Diabetes 49:431-5
Scarpace, P J; Matheny, M; Shek, E W (2000) Impaired leptin signal transduction with age-related obesity. Neuropharmacology 39:1872-9
Scarpace, P J; Matheny, M; Moore, R L et al. (2000) Modulation of uncoupling protein 2 and uncoupling protein 3: regulation by denervation, leptin and retinoic acid treatment. J Endocrinol 164:331-7
Kumar, M V; Moore, R L; Scarpace, P J (1999) Beta3-adrenergic regulation of leptin, food intake, and adiposity is impaired with age. Pflugers Arch 438:681-8
Kumar, M V; Sunvold, G D; Scarpace, P J (1999) Dietary vitamin A supplementation in rats: suppression of leptin and induction of UCP1 mRNA. J Lipid Res 40:824-9
Scarpace, P J; Matheny, M; Tumer, N (1999) Differential down-regulation of beta3-adrenergic receptor mRNA and signal transduction by cold exposure in brown adipose tissue of young and senescent rats. Pflugers Arch 437:479-83
Kumar, M V; Scarpace, P J (1998) Differential effects of retinoic acid on uncoupling protein-1 and leptin gene expression. J Endocrinol 157:237-43

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