Sec Receptor and Alzheimers Disease

Perlmutter, David H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Aging (NIA)
• Type: Research Project (R01)
• Project #: 5R01AG011577-02
• Application #: 2052800
• Study Section: Medical Biochemistry Study Section (MEDB)
• Project Start: 1995-02-05
• Project End: 1998-11-30
• Budget Start: 1995-12-20
• Budget End: 1996-11-30
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Washington University
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 062761671
• City: Saint Louis
• State: MO
• Country: United States
• Zip Code: 63130

Publications

Mazziotti, M; Perlmutter, D H (1998) Resistance to the apoptotic effect of aggregated amyloid-beta peptide in several different cell types including neuronal- and hepatoma-derived cell lines. Biochem J 332 ( Pt 2):517-24

Boland, K; Behrens, M; Choi, D et al. (1996) The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide. J Biol Chem 271:18032-44

Boland, K; Manias, K; Perlmutter, D H (1995) Specificity in recognition of amyloid-beta peptide by the serpin-enzyme complex receptor in hepatoma cells and neuronal cells. J Biol Chem 270:28022-8