Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG013534-02
Application #
2055531
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1995-08-01
Project End
1999-05-31
Budget Start
1996-06-10
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Barnes-Jewish Hospital
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63110

  Publications

Alvarez, Jessica A; Ziegler, Thomas R; Millson, Erin C et al. (2016) Body composition and lung function in cystic fibrosis and their association with adiposity and normal-weight obesity. Nutrition 32:447-52
Cenci, Simone; Toraldo, Gianluca; Weitzmann, M Neale et al. (2003) Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci U S A 100:10405-10
Toraldo, Gianluca; Roggia, Cristiana; Qian, Wei-Ping et al. (2003) IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells. Proc Natl Acad Sci U S A 100:125-30
Weitzmann, M Neale; Roggia, Cristiana; Toraldo, Gianluca et al. (2002) Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest 110:1643-50
Weitzmann, M N; Cenci, S; Rifas, L et al. (2001) T cell activation induces human osteoclast formation via receptor activator of nuclear factor kappaB ligand-dependent and -independent mechanisms. J Bone Miner Res 16:328-37
Weitzmann, M N; Cenci, S; Haug, J et al. (2000) B lymphocytes inhibit human osteoclastogenesis by secretion of TGFbeta. J Cell Biochem 78:318-24
Weitzmann, M N; Cenci, S; Rifas, L et al. (2000) Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines. Blood 96:1873-8
Cenci, S; Weitzmann, M N; Gentile, M A et al. (2000) M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss. J Clin Invest 105:1279-87
Srivastava, S; Weitzmann, M N; Kimble, R B et al. (1998) Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1. J Clin Invest 102:1850-9
Kimble, R B; Bain, S; Pacifici, R (1997) The functional block of TNF but not of IL-6 prevents bone loss in ovariectomized mice. J Bone Miner Res 12:935-41

Showing the most recent 10 out of 13 publications