Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
1R01AG013956-01
Application #
2055903
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1996-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Neurology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Han, Byung Hee; Zhou, Meng-Liang; Johnson, Andrew W et al. (2015) Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice. Proc Natl Acad Sci U S A 112:E881-90
Kim, Jaekwang; Yoon, Hyejin; Horie, Takahiro et al. (2015) microRNA-33 Regulates ApoE Lipidation and Amyloid-? Metabolism in the Brain. J Neurosci 35:14717-26
Shin, Soomin; Walz, Katharine A; Archambault, Angela S et al. (2014) Apolipoprotein E mediation of neuro-inflammation in a murine model of multiple sclerosis. J Neuroimmunol 271:8-17
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Castellano, Joseph M; Deane, Rashid; Gottesdiener, Andrew J et al. (2012) Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood A? clearance in a mouse model of ?-amyloidosis. Proc Natl Acad Sci U S A 109:15502-7
Hashimoto, Tadafumi; Serrano-Pozo, Alberto; Hori, Yukiko et al. (2012) Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid ýý peptide. J Neurosci 32:15181-92
Kim, Jungsu; Eltorai, Adam E M; Jiang, Hong et al. (2012) Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of A? amyloidosis. J Exp Med 209:2149-56

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