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Wilson, Emily L; King, Anne M; Sherwood, Erin M et al. (2005) Pre-B cell loss in senescence coincides with preferential development of immature B cells characterized by partial activation and altered Vh repertoire. Exp Gerontol 40:67-79
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Riley, Richard L; Blomberg, Bonnie B; Frasca, Daniela (2005) B cells, E2A, and aging. Immunol Rev 205:30-47
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Frasca, Daniela; Nguyen, Diep; Riley, Richard L et al. (2004) Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells. Mech Ageing Dev 125:111-2
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Frasca, Daniela; Van der Put, Elaine; Riley, Richard L et al. (2004) Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase. J Immunol 172:2155-62
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Van der Put, Elaine; Frasca, Daniela; King, Anne M et al. (2004) Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover. J Immunol 173:818-27
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Frasca, Daniela; Van Der Put, Elaine; Riley, Richard L et al. (2004) Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells. Exp Gerontol 39:481-9
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Sherwood, Erin M; Xu, Wei; Riley, Richard L (2003) B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered expression of Bcl-2 family members. Mech Ageing Dev 124:147-53
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Wilson, Emily L; Sherwood, Erin M; King, Anne M et al. (2003) A phenotypically distinct subset of immature B cells exhibits partial activation, increased survival, and preferential expression of VhS107. Eur J Immunol 33:3398-408
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Frasca, Daniela; Nguyen, Diep; Van der Put, Elaine et al. (2003) The age-related decrease in E47 DNA-binding does not depend on increased Id inhibitory proteins in bone marrow-derived B cell precursors. Front Biosci 8:a110-6
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Frasca, Daniela; Nguyen, Diep; Riley, Richard L et al. (2003) Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. J Immunol 170:719-26
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