Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG021661-02
Application #
6698815
Study Section
Special Emphasis Panel (ZRG1-BDCN-3 (01))
Program Officer
Snyder, Stephen D
Project Start
2003-02-01
Project End
2007-11-30
Budget Start
2004-01-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$302,927
Indirect Cost
Name
Northwestern University at Chicago
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Lagalwar, Sarita; Berry, Robert W; Binder, Lester I (2007) Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies. Acta Neuropathol 113:63-73
Ginsberg, Stephen D; Che, Shaoli; Wuu, Joanne et al. (2006) Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease. J Neurochem 97:475-87
Guillozet-Bongaarts, Angela L; Cahill, Michael E; Cryns, Vincent L et al. (2006) Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo. J Neurochem 97:1005-14
Lagalwar, Sarita; Guillozet-Bongaarts, Angela L; Berry, Robert W et al. (2006) Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease. J Neuropathol Exp Neurol 65:455-64
Ginsberg, Stephen D; Che, Shaoli; Counts, Scott E et al. (2006) Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. J Neurochem 96:1401-8
Reynolds, Matthew R; Reyes, Juan F; Fu, Yifan et al. (2006) Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies. J Neurosci 26:10636-45
Sengupta, Soma; Horowitz, Peleg M; Karsten, Stanislav L et al. (2006) Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry 45:15111-9
Guillozet-Bongaarts, Angela L; Garcia-Sierra, Francisco; Reynolds, Matthew R et al. (2005) Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease. Neurobiol Aging 26:1015-22
Binder, Lester I; Guillozet-Bongaarts, Angela L; Garcia-Sierra, Francisco et al. (2005) Tau, tangles, and Alzheimer's disease. Biochim Biophys Acta 1739:216-23
Horowitz, Peleg M; Patterson, Kristina R; Guillozet-Bongaarts, Angela L et al. (2004) Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. J Neurosci 24:7895-902

Showing the most recent 10 out of 11 publications