Combined aerobic and resistance training have unique benefits for maintaining a physical activity (PA). However, the optimal training program for combining these two modes of training in older adults is unknown. This study builds on current and past studies showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are important for maintaining an active lifestyle, a favorable body composition, and high bone density. Traditionally 3 d/wk combined training has been felt to be optimal while recent studies suggest 1 d/wk combined training may create similar adaptations as more frequent training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that 3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE). We hypothesize that C2 will result in a larger increase in muscle size, bone density, strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating cytokinejs andpsychological mood states linked to chronic overstress will also be examined. Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks training. Design: We will to evaluate 78 (>60 yrs) Black and White women matched for age, race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women will undergo evaluation of metabolic parameters in a General Clinical ResearchCenter. Significance: This study should provide insight into the effects combined training frequency has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG027084-04S1
Application #
7624538
Study Section
Integrative Physiology of Obesity and Diabetes Study Section (IPOD)
Program Officer
Stahl, Sidney M
Project Start
2008-09-01
Project End
2010-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
4
Fiscal Year
2008
Total Cost
$131,088
Indirect Cost
Name
University of Alabama Birmingham
Department
Miscellaneous
Type
Schools of Education
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Hunter, Gary R; Bryan, David R; Borges, Juliano H et al. (2018) Racial Differences in Relative Skeletal Muscle Mass Loss During Diet-Induced Weight Loss in Women. Obesity (Silver Spring) 26:1255-1260
Hunter, Gary R; Fisher, Gordon; Bryan, David R et al. (2018) Divergent Blood Pressure Response After High-Intensity Interval Exercise: A Signal of Delayed Recovery? J Strength Cond Res 32:3004-3010
Carter, Stephen J; Plaisance, Eric P; Fisher, Gordon et al. (2017) Alterations in Hemoglobin and Serum 25-hydroxyvitamin D are Related Before and After Weight Loss Independent of African Admixture. Int J Sport Nutr Exerc Metab 27:59-66
Hunter, Gary R; Moellering, Douglas R; Carter, Stephen J et al. (2017) Potential Causes of Elevated REE after High-Intensity Exercise. Med Sci Sports Exerc 49:2414-2421
Hunter, Gary R; Fisher, Gordon; Neumeier, William H et al. (2015) Exercise Training and Energy Expenditure following Weight Loss. Med Sci Sports Exerc 47:1950-7
Hunter, Gary R; Neumeier, William H; Bickel, C Scott et al. (2014) Arterial elasticity, strength, fatigue, and endurance in older women. Biomed Res Int 2014:501754
Hunter, Gary R; Plaisance, Eric P; Fisher, Gordon (2014) Weight loss and bone mineral density. Curr Opin Endocrinol Diabetes Obes 21:358-62
Ellis, Amy C; Alvarez, Jessica A; Gower, Barbara A et al. (2014) Cardiorespiratory fitness in older adult women: relationships with serum 25-hydroxyvitamin D. Endocrine 47:839-44
Fisher, Gordon; Bickel, C Scott; Hunter, Gary R (2014) Elevated Circulating TNF-? in Fat-Free Mass Non-Responders Compared to Responders Following Exercise Training in Older Women. Biology (Basel) 3:551-9
Fisher, Gordon; Hunter, Gary R; Glasser, Stephen P (2013) Associations between arterial elasticity and markers of inflammation in healthy older women. J Gerontol A Biol Sci Med Sci 68:382-8

Showing the most recent 10 out of 17 publications